exercise performance

Alpha Lipoic Acid Exercise Performance Randomized Trial Evidence Table

Structured evidence table for Alpha Lipoic Acid Exercise Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Alpha Lipoic Acid Exercise Performance Randomized TrialBackground/Objectives : This study aimed to evaluate the effects of four weeks of combined Acetyl-l-Carnitine and alpha-lipoic acid (ALA) supplementation on anaerobic and aerobic performance and fatigue resistance in trained cyclists, hypothesizing improvements in maximal aerobic power (MAP), Wingate test performance, and reduced lactate accumulation.4de Rozas A (2025)l-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration.
Alpha Lipoic Acid Exercise Performance Randomized TrialResults : MAP increased by 3.4% (314 ± 32 W to 324 ± 37 W; p = 0.005) with no group interaction ( p = 0.457).4de Rozas A (2025)l-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration.
Alpha Lipoic Acid Exercise Performance Randomized TrialMethods : In a double-blind, randomized trial, 41 male trained cyclists (age: 36 ± 12 years; MAP: 4.35 ± 0.60 W·kg -1 ) were assigned to a supplement group (SUP, n = 19; 1200 mg/day Acetyl-l-Carnitine, 300 mg/day ALA, 1.1 mg Vitamin B1, 2.5 µg Vitamin B12) or placebo group (PLA, n = 22) for four weeks.4de Rozas A (2025)l-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration.
Alpha Lipoic Acid Exercise Performance Randomized TrialIn addition to muscle damage and inflammation, intense training can cause oxidative stress due to increased radical formation of hydrogen peroxide (HO), superoxide (O), hypochlorous acid (HOCl) and nitric oxide (NO) [].4Isenmann Eduard (2020)The effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training
Alpha Lipoic Acid Exercise Performance Randomized TrialIn the following warm-up sets, the weight was increased by about 10–20% and the repetition number reduced to five and three repetitions.4Isenmann Eduard (2020)The effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training
Alpha Lipoic Acid Exercise Performance Randomized Trial3 3 3 3 A total of eight subjects (P1, P7, P8, P13, P14, P15, P16, P17) with ALA supplementation improved their performance after the six-day protocol.4Isenmann Eduard (2020)The effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training
Alpha Lipoic Acid Exercise Performance Randomized Trial1 3 In competitive sports, the time span needed for muscle recovery plays a decisive role.4Isenmann Eduard (2020)The effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training
topicAlpha Lipoic Acid Exercise Performance Randomized Trial
claimBackground/Objectives : This study aimed to evaluate the effects of four weeks of combined Acetyl-l-Carnitine and alpha-lipoic acid (ALA) supplementation on anaerobic and aerobic performance and fatigue resistance in trained cyclists, hypothesizing improvements in maximal aerobic power (MAP), Wingate test performance, and reduced lactate accumulation.
evidence level4
citationde Rozas A (2025)
sourcel-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration.
topicAlpha Lipoic Acid Exercise Performance Randomized Trial
claimResults : MAP increased by 3.4% (314 ± 32 W to 324 ± 37 W; p = 0.005) with no group interaction ( p = 0.457).
evidence level4
citationde Rozas A (2025)
sourcel-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration.
topicAlpha Lipoic Acid Exercise Performance Randomized Trial
claimMethods : In a double-blind, randomized trial, 41 male trained cyclists (age: 36 ± 12 years; MAP: 4.35 ± 0.60 W·kg -1 ) were assigned to a supplement group (SUP, n = 19; 1200 mg/day Acetyl-l-Carnitine, 300 mg/day ALA, 1.1 mg Vitamin B1, 2.5 µg Vitamin B12) or placebo group (PLA, n = 22) for four weeks.
evidence level4
citationde Rozas A (2025)
sourcel-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration.
topicAlpha Lipoic Acid Exercise Performance Randomized Trial
claimIn addition to muscle damage and inflammation, intense training can cause oxidative stress due to increased radical formation of hydrogen peroxide (HO), superoxide (O), hypochlorous acid (HOCl) and nitric oxide (NO) [].
evidence level4
citationIsenmann Eduard (2020)
sourceThe effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training
topicAlpha Lipoic Acid Exercise Performance Randomized Trial
claimIn the following warm-up sets, the weight was increased by about 10–20% and the repetition number reduced to five and three repetitions.
evidence level4
citationIsenmann Eduard (2020)
sourceThe effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training
topicAlpha Lipoic Acid Exercise Performance Randomized Trial
claim3 3 3 3 A total of eight subjects (P1, P7, P8, P13, P14, P15, P16, P17) with ALA supplementation improved their performance after the six-day protocol.
evidence level4
citationIsenmann Eduard (2020)
sourceThe effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training
topicAlpha Lipoic Acid Exercise Performance Randomized Trial
claim1 3 In competitive sports, the time span needed for muscle recovery plays a decisive role.
evidence level4
citationIsenmann Eduard (2020)
sourceThe effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training

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Source documents

  1. l-Carnitine and Alpha-Lipoic Acid Fail to Improve Anaerobic and Aerobic Performance in Trained Cyclists Despite a Reduction in Blood Lactate Concentration.
  2. The effects of alpha lipoic acid on muscle strength recovery after a single and a short-term chronic supplementation - a study in healthy well-trained individuals after intensive resistance and endurance training