Does Theanine Anxiety Randomized Trial work?

The current Migaku evidence database contains 1 reusable source document for Theanine Anxiety Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove. - Results : The mean THI score decreased from 40.8 at baseline to 30.9 at the end of the study ( p = 0.012), and the percentage of patients with THI grade 1 (no handicap) increased from 3.3% to 20%. [Cepeda Uceta M (2026); evidence level 3] - A decrease in the mean frequency of tinnitus from 2417.4 Hz to 1603.3 Hz ( p = 0.519) was found. [Cepeda Uceta M (2026); evidence level 3] - Conclusions : The administration of a natural-based dietary supplement composed of L-theanine, Ginkgo biloba , melatonin, GABA, zinc, selenium, and group B vitamins during 90 days in patients with tinnitus was associated with a significant increase in QoL by reducing tinnitus-associated handicap and anxiety. [Cepeda Uceta M (2026); evidence level 3] - Background/Objectives : The objective of the study was to assess the benefits on quality of life (QoL) of a natural-based dietary supplement in patients with tinnitus. [Cepeda Uceta M (2026); evidence level 3] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.