topicApigenin Anxiety Randomized Trial
claim2 3 4 5 6 7 1 8 Flavonoids are a diverse class of plant-derived polyphenols found abundantly in fruits, vegetables, wine, tea, and cocoa [,,].
evidence level4
citationRosas-Sánchez Gilberto Uriel (2026)
sourceFlavonoids as Modulators of Neuroinflammation in Affective Disorders: A Narrative Review
topicApigenin Anxiety Randomized Trial
claimFor example, curcumin, found in turmeric, has demonstrated neuroprotective, anti-inflammatory, antioxidant, and antidepressant effects [,].
evidence level4
citationRosas-Sánchez Gilberto Uriel (2026)
sourceFlavonoids as Modulators of Neuroinflammation in Affective Disorders: A Narrative Review
topicApigenin Anxiety Randomized Trial
claimIt affects approximately 1–4% of the global population and is associated with significant functional impairment and increased mortality [,].
evidence level4
citationRosas-Sánchez Gilberto Uriel (2026)
sourceFlavonoids as Modulators of Neuroinflammation in Affective Disorders: A Narrative Review
topicApigenin Anxiety Randomized Trial
claim1 Given the fundamental role of neuroinflammation in affective disorders, there is growing interest in natural compounds, particularly flavonoids and polyphenols, for their potential to modulate inflammation and support brain function [].
evidence level4
citationRosas-Sánchez Gilberto Uriel (2026)
sourceFlavonoids as Modulators of Neuroinflammation in Affective Disorders: A Narrative Review