Does Spirulina Muscle Endurance Randomized Trial work?

Updated October 2026

Quick Answer

Spirulina Muscle Endurance Randomized Trial has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Such conditions expose muscle tissue to structural damage, increased production of reactive oxygen species (ROS), and disruption of fibre integrity [,].

Key Takeaways

  • 01Such conditions expose muscle tissue to structural damage, increased production of reactive oxygen species (ROS), and disruption of fibre integrity [,]. [Azizi Ammarati Amir Hossein (2026)]
  • 022 4 5 6 The biological consequences of this physical load include elevated markers of muscle damage such as creatine kinase (CK) and lactate dehydrogenase (LDH), increased lipid peroxidation products such as malondialdehyde (MDA), and systemic inflammatory responses characterised by elevated interleukin-6 (IL-6) and C-reactive protein (CRP). [Azizi Ammarati Amir Hossein (2026)]
  • 03Recent systematic reviews indicate that supplements such as melatonin may reduce oxidative and inflammatory markers in athletes; however, evidence regarding consistent and direct improvements in performance parameters remains conflicting []. [Azizi Ammarati Amir Hossein (2026)]
  • 041 2 3 Soccer, as an intermittent team sport, integrates prolonged walking and running with brief bursts of explosive sprinting and repeated anaerobic efforts. [Azizi Ammarati Amir Hossein (2026)]
The current Migaku evidence database contains 2 reusable source documents for Spirulina Muscle Endurance Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove. - Such conditions expose muscle tissue to structural damage, increased production of reactive oxygen species (ROS), and disruption of fibre integrity [,]. [Azizi Ammarati Amir Hossein (2026); evidence level 4] - 2 4 5 6 The biological consequences of this physical load include elevated markers of muscle damage such as creatine kinase (CK) and lactate dehydrogenase (LDH), increased lipid peroxidation products such as malondialdehyde (MDA), and systemic inflammatory responses characterised by elevated interleukin-6 (IL-6) and C-reactive protein (CRP). [Azizi Ammarati Amir Hossein (2026); evidence level 4] - Recent systematic reviews indicate that supplements such as melatonin may reduce oxidative and inflammatory markers in athletes; however, evidence regarding consistent and direct improvements in performance parameters remains conflicting []. [Azizi Ammarati Amir Hossein (2026); evidence level 4] - 1 2 3 Soccer, as an intermittent team sport, integrates prolonged walking and running with brief bursts of explosive sprinting and repeated anaerobic efforts. [Azizi Ammarati Amir Hossein (2026); evidence level 4] - ® 2+ 2+ 2+ + 2+ 29 After a week of adaptation, the animals fed with the standard diet A04 (SAFE, Augy, France) were randomly divided into four groups of eight rats according to their running capacity and food supplement associated with diet. [Vignaud Jordi (2025); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Mechanism-based nutritional strategies for performance and recovery in soccer players: a qualitative research synthesis
  2. Combined Effects of Spirulina Liquid Extract and Endurance Training on Aerobic Performance and Muscle Metabolism Adaptation in Wistar Rats