topicUrolithin A Muscle Endurance Randomized Trial
claimBackground Urolithin A (UA), a gut microbiota-derived metabolite, has been proposed to improve skeletal muscle function, but evidence from randomized controlled trials has not been systematically summarized.
evidence level2
citationDao T (2026)
sourceEffects of Urolithin A supplementation on muscle health outcomes in humans from randomized controlled trials.
topicUrolithin A Muscle Endurance Randomized Trial
claimRisk of bias was assessed using the Cochrane Risk of Bias 2 (RoB 2) tool, and the certainty of evidence for the primary quantitatively synthesized outcome was rated using the GRADE approach.
evidence level2
citationDao T (2026)
sourceEffects of Urolithin A supplementation on muscle health outcomes in humans from randomized controlled trials.
topicUrolithin A Muscle Endurance Randomized Trial
claimConclusion The currently available randomized human evidence is limited to five small, short-term trials in clinically heterogeneous populations.
evidence level2
citationDao T (2026)
sourceEffects of Urolithin A supplementation on muscle health outcomes in humans from randomized controlled trials.
topicUrolithin A Muscle Endurance Randomized Trial
claimThis systematic review and meta-analysis aimed to evaluate the effects of UA supplementation on muscle performance as well as biochemical and mitochondrial biomarkers in humans.
evidence level2
citationDao T (2026)
sourceEffects of Urolithin A supplementation on muscle health outcomes in humans from randomized controlled trials.