Does Spirulina Endurance Randomized Trial work?

Updated October 2026

Quick Answer

Spirulina Endurance Randomized Trial has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Red Cell Distribution Width significantly increased following spirulina supplementation in comparison to placebo (spirulina = 13.3 ± 0.9 % vs.

Key Takeaways

  • 01Red Cell Distribution Width significantly increased following spirulina supplementation in comparison to placebo (spirulina = 13.3 ± 0.9 % vs. [Gurney T (2025)]
  • 02Conclusion In conclusion, three weeks of spirulina supplementation at 6 g/day reduced heart rate during a lactate threshold test at a simulated moderate altitude (2,500 m), but did not produce additional physiological or hematological benefits. [Gurney T (2025)]
  • 03Background Existing literature indicates that spirulina supplementation can improve a variety of blood morphological parameters (such as hemoglobin) in healthy and clinical populations. [Gurney T (2025)]
  • 04Given the importance of hemoglobin for endurance exercise, particularly at altitude, this study aimed to investigate whether spirulina supplementation can improve blood morphological parameters in healthy cyclists and positively influence physiological variables when completing a lactate threshold test at simulated moderate altitude (2,500 m). [Gurney T (2025)]
The current Migaku evidence database contains 2 reusable source documents for Spirulina Endurance Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove. - Red Cell Distribution Width significantly increased following spirulina supplementation in comparison to placebo (spirulina = 13.3 ± 0.9 % vs. [Gurney T (2025); evidence level 2] - Conclusion In conclusion, three weeks of spirulina supplementation at 6 g/day reduced heart rate during a lactate threshold test at a simulated moderate altitude (2,500 m), but did not produce additional physiological or hematological benefits. [Gurney T (2025); evidence level 2] - Background Existing literature indicates that spirulina supplementation can improve a variety of blood morphological parameters (such as hemoglobin) in healthy and clinical populations. [Gurney T (2025); evidence level 2] - Given the importance of hemoglobin for endurance exercise, particularly at altitude, this study aimed to investigate whether spirulina supplementation can improve blood morphological parameters in healthy cyclists and positively influence physiological variables when completing a lactate threshold test at simulated moderate altitude (2,500 m). [Gurney T (2025); evidence level 2] - Background Physical activity, such as running, protects against cardiovascular disease and obesity but can induce oxidative stress. [Vignaud J (2025); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Physiological effects of spirulina supplementation during lactate threshold exercise at simulated altitude (2,500 m): a randomized controlled trial.
  2. Combined Effects of Spirulina Liquid Extract and Endurance Training on Aerobic Performance and Muscle Metabolism Adaptation in Wistar Rats.