Is Sam-E Mood Meta-Analysis safe?

The current Migaku evidence database contains 2 reusable source documents for Sam-E Mood Meta-Analysis. This answer focuses on safety, limits, and clinician-discussion contexts. - Exposure to nature has been associated with benefits to human well-being, commonly evaluated using standardized psychological assessments and, more recently, neuroimaging modalities such as Electroencephalography (EEG), functional Magnetic Resonance Imaging (fMRI), and functional Near-Infrared Spectroscopy (fNIRS). [Daube A (2026); evidence level 1] - Overall, exposure to nature was associated with reductions in negative emotions in clinical populations. [Daube A (2026); evidence level 1] - In contrast, healthy populations showed a more balanced psychological response, with nature exposure being associated with both increases in positive emotions and reductions in negative emotions. [Daube A (2026); evidence level 1] - (1) How is the impact of nature on well-being studied using psychological and neuroimaging modalities and what does it reveal? [Daube A (2026); evidence level 1] - Background Adolescent anxiety is a growing public health concern associated with significant social and emotional impairment. [Yu CTK (2026); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.