supplement evidence

What does the evidence say about Prune Bone Mineral Density Randomized Trial?

Updated October 2026

Quick Answer

Prune Bone Mineral Density Randomized Trial has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: Dropout was 22%; however, the dropout rate was 41% for the 100 g Prune group compared to other groups (10% Control; 15% 50 g Prune; (p Conclusions A 50 g dose of daily dose of prunes can prevent loss of total hip BMD in postmenopausal women, without increased fat mass seen with the larger dose.

Key Takeaways

  • 01Dropout was 22%; however, the dropout rate was 41% for the 100 g Prune group compared to other groups (10% Control; 15% 50 g Prune; (p Conclusions A 50 g dose of daily dose of prunes can prevent loss of total hip BMD in postmenopausal women, without increased fat mass seen with the larger dose. [Low Dose Daily Prunes Preserve Hip Bone Mineral Density With No Impact on Body Composition in a 12-Month Randomized Controlled Trial in Postmenopausal Women: The Prune Study (2022)]
  • 02Abstract Objectives Dietary consumption of prunes has favorable impacts on bone health, however, more research is necessary to improve upon study designs and refine our understandings and determine whether unfavorable fat gain occurs with long-term treatment. [Low Dose Daily Prunes Preserve Hip Bone Mineral Density With No Impact on Body Composition in a 12-Month Randomized Controlled Trial in Postmenopausal Women: The Prune Study (2022)]
  • 03Objectives: Evaluate the effects of prunes (50g and 100g/day) on bone mineral density (BMD) in postmenopausal women during a 12-month dietary intervention. [Low Dose Daily Prunes Preserve Hip Bone Mineral Density With No Impact on Body Composition in a 12-Month Randomized Controlled Trial in Postmenopausal Women: The Prune Study (2022)]
  • 04These findings provide evidence that postmenopausal women with initial low BMD can benefit from prunes if they host certain gut microbes. [Simpson AMR (2024)]
The current Migaku evidence database contains 2 reusable source documents for Prune Bone Mineral Density Randomized Trial. This answer focuses on benefits, uncertainty, and practical interpretation. - Dropout was 22%; however, the dropout rate was 41% for the 100 g Prune group compared to other groups (10% Control; 15% 50 g Prune; (p Conclusions A 50 g dose of daily dose of prunes can prevent loss of total hip BMD in postmenopausal women, without increased fat mass seen with the larger dose. [Low Dose Daily Prunes Preserve Hip Bone Mineral Density With No Impact on Body Composition in a 12-Month Randomized Controlled Trial in Postmenopausal Women: The Prune Study (2022); evidence level 2] - Abstract Objectives Dietary consumption of prunes has favorable impacts on bone health, however, more research is necessary to improve upon study designs and refine our understandings and determine whether unfavorable fat gain occurs with long-term treatment. [Low Dose Daily Prunes Preserve Hip Bone Mineral Density With No Impact on Body Composition in a 12-Month Randomized Controlled Trial in Postmenopausal Women: The Prune Study (2022); evidence level 2] - Objectives: Evaluate the effects of prunes (50g and 100g/day) on bone mineral density (BMD) in postmenopausal women during a 12-month dietary intervention. [Low Dose Daily Prunes Preserve Hip Bone Mineral Density With No Impact on Body Composition in a 12-Month Randomized Controlled Trial in Postmenopausal Women: The Prune Study (2022); evidence level 2] - These findings provide evidence that postmenopausal women with initial low BMD can benefit from prunes if they host certain gut microbes. [Simpson AMR (2024); evidence level 4] - Foods high in phenolics such as prunes have been shown to exert protective effects on bone mineral density (BMD), but only certain individuals experience these benefits. [Simpson AMR (2024); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

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Sources

  1. Low Dose Daily Prunes Preserve Hip Bone Mineral Density With No Impact on Body Composition in a 12-Month Randomized Controlled Trial in Postmenopausal Women: The Prune Study
  2. Gut microbes differ in postmenopausal women responding to prunes to maintain hip bone mineral density.