topicPrune Bone Health Randomized Trial
claim1 2 3 4 1 3 5 6 7 7 8 Osteoporosis is a debilitating degenerative disease characterized by decreases in bone mineral density (BMD) and quality, thereby increasing the risk of fractures, decreasing activities of daily living, and consequently raising the risk of morbidity and mortality [,,,].
evidence level2
citationOrmsbee Lauren T. (2026)
sourcePrune Consumption and Bone Health in Older Men: A One-Year Randomized Controlled Trial
topicPrune Bone Health Randomized Trial
claim11 12 13 11 13 14 15 16 17 14 18 19 11 12 17 12 There is ample evidence to support that certain fruits and vegetables contain various cardiovascular and bone-protective polyphenols that combat damaging free radicals, thus aiding in the reduction of chronic inflammation [,,].
evidence level2
citationOrmsbee Lauren T. (2026)
sourcePrune Consumption and Bone Health in Older Men: A One-Year Randomized Controlled Trial
topicPrune Bone Health Randomized Trial
claimRegarding osteoporosis and bone health, there is evidence to support prunes’ bone-protective effects in animal models, as demonstrated by Muhlbauer et al.
evidence level2
citationOrmsbee Lauren T. (2026)
sourcePrune Consumption and Bone Health in Older Men: A One-Year Randomized Controlled Trial
topicPrune Bone Health Randomized Trial
claimIn the United States, approximately 53.4 million individuals aged 50 or older suffer from low bone mass.
evidence level2
citationOrmsbee Lauren T. (2026)
sourcePrune Consumption and Bone Health in Older Men: A One-Year Randomized Controlled Trial
topicPrune Bone Health Randomized Trial
claim1 2 1 3 Following peak bone mass attainment, bone mass decreases with age, with an accelerated bone loss occurring after menopause, and the risk of osteoporotic fractures increases [].
evidence level4
citationRizzoli René (2024)
sourceBone health: biology and nutrition
topicPrune Bone Health Randomized Trial
claimThe lifetime risk of sustaining an osteoporotic fracture is around 50% for women and 20% for men by the age of 50 years.
evidence level4
citationRizzoli René (2024)
sourceBone health: biology and nutrition
topicPrune Bone Health Randomized Trial
claimIndeed, there is a large body of evidence linking nutritional intake to bone growth and bone loss later in life, both of which influence fracture risk (Fig.).
evidence level4
citationRizzoli René (2024)
sourceBone health: biology and nutrition