Prune Bone Density Randomized Trial Evidence Table

Structured evidence table for Prune Bone Density Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Prune Bone Density Randomized TrialObjectives: The purpose of the present systematic review was to summarize the evidence from the randomized controlled studies on the effect of prunes on bone health in humans and to pool the results in a meta-analysis.1Treister-Goltzman Y (2026)Effects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Prune Bone Density Randomized TrialThe effect of prune intervention in postmenopausal women was borderline significant at the lumbar spine, with BMD slightly higher in the intervention group (SMD [95% CI] = 1.30 [-0.03, 2.63]; I 2 = 98%; p Conclusions: Our meta-analysis provides preliminary evidence of modest skeletal benefits associated with consumption of 50-100 g of prunes, particularly at the lumbar spine, a trabecular-rich site.1Treister-Goltzman Y (2026)Effects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Prune Bone Density Randomized TrialBackground: Recent studies suggest that prunes are one of the most effective fruits for preventing and reversing bone loss.1Treister-Goltzman Y (2026)Effects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Prune Bone Density Randomized TrialAdditionally, it is currently unknown whether various prune dosages yield comparable or improved effects on bone health parameters during a 12-month investigation.2De Souza Mary Jane (2022)Rationale and study design of Randomized Controlled Trial of Dietary Supplementation with prune (dried plums) on bone density, geometry, and estimated bone strength in postmenopausal women: The Prune study
Prune Bone Density Randomized TrialWomen with previous fracture and severe osteoporosis were excluded from this study, 2) targeting this age range allowed us to generalize our results to postmenopausal women with low bone mass who may experience a high risk for fracture.2De Souza Mary Jane (2022)Rationale and study design of Randomized Controlled Trial of Dietary Supplementation with prune (dried plums) on bone density, geometry, and estimated bone strength in postmenopausal women: The Prune study
Prune Bone Density Randomized TrialFracture risk assessment was determined using the trabecular bone score (TBS)-adjusted FRAX® tool () [,], in which the algorithm computes 10-year probability of major osteoporotic fracture or hip fracture.2De Souza Mary Jane (2022)Rationale and study design of Randomized Controlled Trial of Dietary Supplementation with prune (dried plums) on bone density, geometry, and estimated bone strength in postmenopausal women: The Prune study
Prune Bone Density Randomized Trial1 2 3 [4] [5] [6] [7] By 2030, the prevalence of osteoporosis for women 50 years and older is projected to reach 13.6 million and the prevalence of low bone mass is expected to reach 57.8 million [].2De Souza Mary Jane (2022)Rationale and study design of Randomized Controlled Trial of Dietary Supplementation with prune (dried plums) on bone density, geometry, and estimated bone strength in postmenopausal women: The Prune study
topicPrune Bone Density Randomized Trial
claimObjectives: The purpose of the present systematic review was to summarize the evidence from the randomized controlled studies on the effect of prunes on bone health in humans and to pool the results in a meta-analysis.
evidence level1
citationTreister-Goltzman Y (2026)
sourceEffects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicPrune Bone Density Randomized Trial
claimThe effect of prune intervention in postmenopausal women was borderline significant at the lumbar spine, with BMD slightly higher in the intervention group (SMD [95% CI] = 1.30 [-0.03, 2.63]; I 2 = 98%; p Conclusions: Our meta-analysis provides preliminary evidence of modest skeletal benefits associated with consumption of 50-100 g of prunes, particularly at the lumbar spine, a trabecular-rich site.
evidence level1
citationTreister-Goltzman Y (2026)
sourceEffects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicPrune Bone Density Randomized Trial
claimBackground: Recent studies suggest that prunes are one of the most effective fruits for preventing and reversing bone loss.
evidence level1
citationTreister-Goltzman Y (2026)
sourceEffects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
topicPrune Bone Density Randomized Trial
claimAdditionally, it is currently unknown whether various prune dosages yield comparable or improved effects on bone health parameters during a 12-month investigation.
evidence level2
citationDe Souza Mary Jane (2022)
sourceRationale and study design of Randomized Controlled Trial of Dietary Supplementation with prune (dried plums) on bone density, geometry, and estimated bone strength in postmenopausal women: The Prune study
topicPrune Bone Density Randomized Trial
claimWomen with previous fracture and severe osteoporosis were excluded from this study, 2) targeting this age range allowed us to generalize our results to postmenopausal women with low bone mass who may experience a high risk for fracture.
evidence level2
citationDe Souza Mary Jane (2022)
sourceRationale and study design of Randomized Controlled Trial of Dietary Supplementation with prune (dried plums) on bone density, geometry, and estimated bone strength in postmenopausal women: The Prune study
topicPrune Bone Density Randomized Trial
claimFracture risk assessment was determined using the trabecular bone score (TBS)-adjusted FRAX® tool () [,], in which the algorithm computes 10-year probability of major osteoporotic fracture or hip fracture.
evidence level2
citationDe Souza Mary Jane (2022)
sourceRationale and study design of Randomized Controlled Trial of Dietary Supplementation with prune (dried plums) on bone density, geometry, and estimated bone strength in postmenopausal women: The Prune study
topicPrune Bone Density Randomized Trial
claim1 2 3 [4] [5] [6] [7] By 2030, the prevalence of osteoporosis for women 50 years and older is projected to reach 13.6 million and the prevalence of low bone mass is expected to reach 57.8 million [].
evidence level2
citationDe Souza Mary Jane (2022)
sourceRationale and study design of Randomized Controlled Trial of Dietary Supplementation with prune (dried plums) on bone density, geometry, and estimated bone strength in postmenopausal women: The Prune study

Source documents

  1. Effects of Prunes on Bone Density in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
  2. Rationale and study design of Randomized Controlled Trial of Dietary Supplementation with prune (dried plums) on bone density, geometry, and estimated bone strength in postmenopausal women: The Prune study