Is Pineapple Bromelain Recovery Randomized Trial safe?

Updated October 2026

Quick Answer

Pineapple Bromelain Recovery Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: Bromelain, a proteolytic enzyme found naturally in pineapple, including its by-products, may positively influence the bioaccessibility of phenolics from milk coffee.

Key Takeaways

  • 01Bromelain, a proteolytic enzyme found naturally in pineapple, including its by-products, may positively influence the bioaccessibility of phenolics from milk coffee. [Kocakaplan ZB (2024)]
  • 02The results showed that incorporating extracts from the crown or core in both black and milk coffee increased the bioaccessibility of total phenolics (from 93 to 114% to 105-129%) and antioxidants (from 54 to 56% to 84-87%), while this effect was not observed for the shell. [Kocakaplan ZB (2024)]
  • 03The industrial processing of pineapples generates a substantial quantity of by-products, including shell, crown, and core. [Kocakaplan ZB (2024)]
  • 04The bromelain powders from the crowns did not show significant enzymatic activity ( p p < 0.05) reduced the enzymatic activity of the bromelain powders. [Chiarelli PG (2024)]
The current Migaku evidence database contains 2 reusable source documents for Pineapple Bromelain Recovery Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts. - Bromelain, a proteolytic enzyme found naturally in pineapple, including its by-products, may positively influence the bioaccessibility of phenolics from milk coffee. [Kocakaplan ZB (2024); evidence level 4] - The results showed that incorporating extracts from the crown or core in both black and milk coffee increased the bioaccessibility of total phenolics (from 93 to 114% to 105-129%) and antioxidants (from 54 to 56% to 84-87%), while this effect was not observed for the shell. [Kocakaplan ZB (2024); evidence level 4] - The industrial processing of pineapples generates a substantial quantity of by-products, including shell, crown, and core. [Kocakaplan ZB (2024); evidence level 4] - The bromelain powders from the crowns did not show significant enzymatic activity ( p p < 0.05) reduced the enzymatic activity of the bromelain powders. [Chiarelli PG (2024); evidence level 4] - Pineapple by-products are good sources of bromelain, a complex enzyme with commercial applications. [Chiarelli PG (2024); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Valorization of Pineapple (Ananas comosus) By-Products in Milk Coffee Beverage: Influence on Bioaccessibility of Phenolic Compounds.
  2. Enhancing Bromelain Recovery from Pineapple By-Products: A Sustainable Approach for Value Addition and Waste Reduction.