Is Magnesium Glycinate Insomnia Randomized Trial safe?

Updated July 2026

Quick Answer

Magnesium Glycinate Insomnia Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: Small sample size Short duration High Insomnia 11 Tunc et al 2023 938 279/659 81.1 / R ISI, ESS Elderly outpatient patients / / Hypomagnesemia is Associated with EDS Unknown if EDS leads to hypomagnesemia or vice versa.

Key Takeaways

  • 01Small sample size Short duration High Insomnia 11 Tunc et al 2023 938 279/659 81.1 / R ISI, ESS Elderly outpatient patients / / Hypomagnesemia is Associated with EDS Unknown if EDS leads to hypomagnesemia or vice versa. [He Caijun (2025)]
  • 02Low levels were associated with a higher CRP concentration in patients with OSA. [He Caijun (2025)]
  • 03In accordance with the International Classification of Sleep Disorders, sleep disorders fall into seven primary categories: insomnia, sleep-related breathing disorders, central disorders of hypersomnolence, circadian rhythm sleep-wake disorders, sleep-related movement disorders, parasomnias, and other sleep disorders.Sleep and sleep disorders are associated with multiple factors. [He Caijun (2025)]
  • 041 2 3 4 + + + + + + + Magnesium (Mg), the second most abundant mineral in the human body, participates in over 300 biochemical reactions. [He Caijun (2025)]
The current Migaku evidence database contains 2 reusable source documents for Magnesium Glycinate Insomnia Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts. - Small sample size Short duration High Insomnia 11 Tunc et al 2023 938 279/659 81.1 / R ISI, ESS Elderly outpatient patients / / Hypomagnesemia is Associated with EDS Unknown if EDS leads to hypomagnesemia or vice versa. [He Caijun (2025); evidence level 3] - Low levels were associated with a higher CRP concentration in patients with OSA. [He Caijun (2025); evidence level 3] - In accordance with the International Classification of Sleep Disorders, sleep disorders fall into seven primary categories: insomnia, sleep-related breathing disorders, central disorders of hypersomnolence, circadian rhythm sleep-wake disorders, sleep-related movement disorders, parasomnias, and other sleep disorders.Sleep and sleep disorders are associated with multiple factors. [He Caijun (2025); evidence level 3] - 1 2 3 4 + + + + + + + Magnesium (Mg), the second most abundant mineral in the human body, participates in over 300 biochemical reactions. [He Caijun (2025); evidence level 3] - A Nevada PLUS cohort ( n = 15), consisting of high-risk participants with 100% Medicaid coverage, received the intervention virtually. [Stone LP (2026); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. The Mechanisms of Magnesium in Sleep Disorders
  2. A 'Standard of Care PLUS' Model for Preterm Birth Prevention: Integrating Nutrient and Gene Variant Analysis with Targeted Interventions.