Does Elderberry Sleep Randomized Trial work?

Updated July 2026

Quick Answer

Elderberry Sleep Randomized Trial has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: In an exploratory analysis, the temperature-associated rise in nocturnal respiratory rate was significantly attenuated in the NY1301 + DDMP group (group × temperature interaction, p Conclusions: The primary outcome, subjective fatigue assessed using the web-based daily log, was not significantly different between groups during the summer study period.

Key Takeaways

  • 01In an exploratory analysis, the temperature-associated rise in nocturnal respiratory rate was significantly attenuated in the NY1301 + DDMP group (group × temperature interaction, p Conclusions: The primary outcome, subjective fatigue assessed using the web-based daily log, was not significantly different between groups during the summer study period. [Tomizawa M (2026)]
  • 02However, combined intake of NY1301 and DDMP was associated with shorter sleep onset latency, lower pre-task fatigue under standardized conditions, attenuation of the temperature-associated rise in nocturnal respiratory rate, and more pronounced post-stress autonomic recovery during the summer. [Tomizawa M (2026)]
  • 03Objectives: Summer heat can impair sleep and contribute to autonomic dysregulation and fatigue-related symptoms. [Tomizawa M (2026)]
  • 04Because heat exposure may induce oxidative stress and gut-related dysfunction, we hypothesized that combined intake of the probiotic Lacticaseibacillus paracasei subsp. [Tomizawa M (2026)]
The current Migaku evidence database contains 2 reusable source documents for Elderberry Sleep Randomized Trial. This answer focuses on strength of evidence and what the studies can or cannot prove. - In an exploratory analysis, the temperature-associated rise in nocturnal respiratory rate was significantly attenuated in the NY1301 + DDMP group (group × temperature interaction, p Conclusions: The primary outcome, subjective fatigue assessed using the web-based daily log, was not significantly different between groups during the summer study period. [Tomizawa M (2026); evidence level 2] - However, combined intake of NY1301 and DDMP was associated with shorter sleep onset latency, lower pre-task fatigue under standardized conditions, attenuation of the temperature-associated rise in nocturnal respiratory rate, and more pronounced post-stress autonomic recovery during the summer. [Tomizawa M (2026); evidence level 2] - Objectives: Summer heat can impair sleep and contribute to autonomic dysregulation and fatigue-related symptoms. [Tomizawa M (2026); evidence level 2] - Because heat exposure may induce oxidative stress and gut-related dysfunction, we hypothesized that combined intake of the probiotic Lacticaseibacillus paracasei subsp. [Tomizawa M (2026); evidence level 2] - Results Results showed that energy drink group significantly improved repeated sprint performance and showed a potential to attenuate certain aspects of cognitive fatigue. [Liao LA (2026); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Combined NY1301 and DDMP on Sleep and Autonomic Function in Summer: A Randomized Clinical Trial.
  2. Effects of energy drinks on repeated sprint performance and cognitive function in athletes.