What does the evidence say about Creatine Supplementation Cognitive Function Meta-Analysis?

Updated October 2026

Quick Answer

Creatine Supplementation Cognitive Function Meta-Analysis has evidence relevant to benefits, uncertainty, and practical interpretation, but conclusions should stay close to the cited sources. One representative finding is: Commentary: The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis.

Key Takeaways

  • 01Commentary: The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis. [Citherlet T (2026)]
  • 02Results CrM supplementation without exercise training and diet intervention increased lean tissue mass, strength, and muscular endurance while promoting favorable changes in selected blood lipids, HbA1c, and selected markers of cognitive function and memory. [Chun J (2026)]
  • 03Creatine supplementation during an exercise and weight-loss diet intervention increased lean tissue mass, promoted a greater reduction in body fat percentage, and improved muscular strength, endurance, and selected markers of cognitive function and memory. [Chun J (2026)]
  • 04Conclusion CrM supplementation with and without exercise and diet intervention may help middle-aged and older adults maintain muscle mass and strength while favourably affecting selected markers of health and cognitive function. [Chun J (2026)]
The current Migaku evidence database contains 2 reusable source documents for Creatine Supplementation Cognitive Function Meta-Analysis. This answer focuses on benefits, uncertainty, and practical interpretation. - Commentary: The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis. [Citherlet T (2026); evidence level 1] - Results CrM supplementation without exercise training and diet intervention increased lean tissue mass, strength, and muscular endurance while promoting favorable changes in selected blood lipids, HbA1c, and selected markers of cognitive function and memory. [Chun J (2026); evidence level 4] - Creatine supplementation during an exercise and weight-loss diet intervention increased lean tissue mass, promoted a greater reduction in body fat percentage, and improved muscular strength, endurance, and selected markers of cognitive function and memory. [Chun J (2026); evidence level 4] - Conclusion CrM supplementation with and without exercise and diet intervention may help middle-aged and older adults maintain muscle mass and strength while favourably affecting selected markers of health and cognitive function. [Chun J (2026); evidence level 4] - Background Theoretically, CrM supplementation during a weight loss and exercise intervention may help older individuals promote more optimal changes in body composition, training adaptations, and cognition. [Chun J (2026); evidence level 4] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.

Sources

  1. Commentary: The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis.
  2. Effects of creatine supplementation with and without exercise and diet intervention on body composition, cognitive function, and markers of health in middle-aged and older adults.