Is Creatine Cognitive Performance Meta-Analysis safe?

The current Migaku evidence database contains 2 reusable source documents for Creatine Cognitive Performance Meta-Analysis. This answer focuses on safety, limits, and clinician-discussion contexts. - Commentary: The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis. [Citherlet T (2026); evidence level 1] - Creatine is naturally found in red meat and seafood, with trace amounts found in some plants [-]. [Muacevic Alexander (2026); evidence level 3] - About 95% of creatine is found within skeletal muscle, with the remaining 5% in the brain, testes, and heart. [Muacevic Alexander (2026); evidence level 3] - The 2013 National Collegiate Athletic Association (NCAA) National Study of Substance Use Habits of College Student Athletes found that 13.2% used creatine in the last year []. [Muacevic Alexander (2026); evidence level 3] - 1 1 3 4 5 6 3 6 1 4 7 3 Owing to the popularity of nutritional supplements, the orthopedic surgeon will surely encounter patients taking creatine. [Muacevic Alexander (2026); evidence level 3] Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording. This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.