Quick Answer
Citrulline Endurance Performance Meta-Analysis has evidence relevant to strength of evidence and what the studies can or cannot prove, but conclusions should stay close to the cited sources. One representative finding is: Through its involvement in NO-related pathways, L-ARG supplementation has been associated with changes in vascular function and blood flow, which may influence exercise-related physiological responses (,–).
Key Takeaways
- 01Through its involvement in NO-related pathways, L-ARG supplementation has been associated with changes in vascular function and blood flow, which may influence exercise-related physiological responses (,–). [Uçar Halil (2026)]
- 02However, the findings across these studies remain inconsistent, and conclusive evidence supporting clear performance or recovery benefits has yet to be established. [Uçar Halil (2026)]
- 03No significant sequence effect was detected (= 1.08,= 0.393, ηp= 0.213), and no significant period × sequence interaction was observed (= 1.04,= 0.430, ηp= 0.206), indicating no statistically significant evidence of meaningful carryover effects and supporting the adequacy of the 72-h washout period. [Uçar Halil (2026)]
- 041 2 3 Taekwondo is a full-contact martial art in which successful performance is largely determined by the execution of high-force kicking techniques directed to the trunk protector or head of the opponent (,). [Uçar Halil (2026)]
The current Migaku evidence database contains 2 reusable source documents for Citrulline Endurance Performance Meta-Analysis. This answer focuses on strength of evidence and what the studies can or cannot prove.
- Through its involvement in NO-related pathways, L-ARG supplementation has been associated with changes in vascular function and blood flow, which may influence exercise-related physiological responses (,–). [Uçar Halil (2026); evidence level 4]
- However, the findings across these studies remain inconsistent, and conclusive evidence supporting clear performance or recovery benefits has yet to be established. [Uçar Halil (2026); evidence level 4]
- No significant sequence effect was detected (= 1.08,= 0.393, ηp= 0.213), and no significant period × sequence interaction was observed (= 1.04,= 0.430, ηp= 0.206), indicating no statistically significant evidence of meaningful carryover effects and supporting the adequacy of the 72-h washout period. [Uçar Halil (2026); evidence level 4]
- 1 2 3 Taekwondo is a full-contact martial art in which successful performance is largely determined by the execution of high-force kicking techniques directed to the trunk protector or head of the opponent (,). [Uçar Halil (2026); evidence level 4]
- This narrative review synthesizes evidence on naturally derived compounds that influence these pathways, including guayusa, guarana, Alpinia galanga , theobromine, L-citrulline, beetroot extract, cordyceps, and niacin, as well as natural sweeteners such as monk fruit and stevia. [Panda R (2026); evidence level 4]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
This page is educational. People with medical conditions, pregnancy, medication use, or unusual symptoms should ask a qualified clinician before changing supplements, medication, or treatment routines.
Sources