Quick Answer
Ashwagandha Fatigue Randomized Trial has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: Although its safety at conventional doses is well established, evidence regarding the safety of higher doses in healthy adults remains limited.
Key Takeaways
- 01Although its safety at conventional doses is well established, evidence regarding the safety of higher doses in healthy adults remains limited. [Movva N (2026)]
- 02All values remained within reference ranges and were clinically insignificant, with most values slightly reduced except a small increase in alkaline phosphatase. [Movva N (2026)]
- 03Quality of life (SF-36 scores) demonstrated improvement ( p Conclusion High-dose Ashwagandha root extract (2000 mg/day) was well tolerated and demonstrated a favourable safety profile in healthy adults over 12 weeks. [Movva N (2026)]
- 04Background and aim Ashwagandha, adaptogenic herb traditionally used to enhance resilience to stress and promote overall well-being. [Movva N (2026)]
The current Migaku evidence database contains 1 reusable source document for Ashwagandha Fatigue Randomized Trial. This answer focuses on safety, limits, and clinician-discussion contexts.
- Although its safety at conventional doses is well established, evidence regarding the safety of higher doses in healthy adults remains limited. [Movva N (2026); evidence level 4]
- All values remained within reference ranges and were clinically insignificant, with most values slightly reduced except a small increase in alkaline phosphatase. [Movva N (2026); evidence level 4]
- Quality of life (SF-36 scores) demonstrated improvement ( p Conclusion High-dose Ashwagandha root extract (2000 mg/day) was well tolerated and demonstrated a favourable safety profile in healthy adults over 12 weeks. [Movva N (2026); evidence level 4]
- Background and aim Ashwagandha, adaptogenic herb traditionally used to enhance resilience to stress and promote overall well-being. [Movva N (2026); evidence level 4]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
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Sources