Quick Answer
Ashwagandha Cognition Meta-Analysis has evidence relevant to safety, limits, and clinician-discussion contexts, but conclusions should stay close to the cited sources. One representative finding is: Methodological quality and risk of bias were assessed with RoB 2, evidence certainty for each outcome was evaluated with GRADE system, and botanical reporting was assessed with the ConPhyMP checklist.
Key Takeaways
- 01Methodological quality and risk of bias were assessed with RoB 2, evidence certainty for each outcome was evaluated with GRADE system, and botanical reporting was assessed with the ConPhyMP checklist. [Zhu X (2026)]
- 02Ashwagandha significantly improved memory (SMD = 0.52; 95% CI: 0.27-0.78; P 2 = 29.7%), attention and processing speed (SMD = 0.29; 95% CI: 0.07-0.51; P = 0.009; I 2 = 0%), and executive function (SMD = -0.42; 95% CI: -0.70 to -0.13; P = 0.004; I 2 = 37.5%). [Zhu X (2026)]
- 03Visuospatial ability improved after excluding one heterogeneous study (SMD = 0.39; 95% CI: 0.08-0.70; P = 0.013; I 2 = 0%). [Zhu X (2026)]
- 04Background This study aimed to systematically review and evaluate the effects of Withania somnifera (L.) Dunal (Solanaceae) supplementation on cognitive and physical function in adults by meta-analysis. [Zhu X (2026)]
The current Migaku evidence database contains 2 reusable source documents for Ashwagandha Cognition Meta-Analysis. This answer focuses on safety, limits, and clinician-discussion contexts.
- Methodological quality and risk of bias were assessed with RoB 2, evidence certainty for each outcome was evaluated with GRADE system, and botanical reporting was assessed with the ConPhyMP checklist. [Zhu X (2026); evidence level 1]
- Ashwagandha significantly improved memory (SMD = 0.52; 95% CI: 0.27-0.78; P 2 = 29.7%), attention and processing speed (SMD = 0.29; 95% CI: 0.07-0.51; P = 0.009; I 2 = 0%), and executive function (SMD = -0.42; 95% CI: -0.70 to -0.13; P = 0.004; I 2 = 37.5%). [Zhu X (2026); evidence level 1]
- Visuospatial ability improved after excluding one heterogeneous study (SMD = 0.39; 95% CI: 0.08-0.70; P = 0.013; I 2 = 0%). [Zhu X (2026); evidence level 1]
- Background This study aimed to systematically review and evaluate the effects of Withania somnifera (L.) Dunal (Solanaceae) supplementation on cognitive and physical function in adults by meta-analysis. [Zhu X (2026); evidence level 1]
- Many reviews suggest multiple biological activities, often based on preclinical evidence concerning WS. [Pandey Sudip (2026); evidence level 4]
Evidence levels are sorting aids, not final clinical grades. Level 1 usually indicates systematic-review style evidence, level 2 indicates randomized trials or public-health guidance, and lower levels need more cautious wording.
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Sources