Zinc Supplementation Evidence Table

Structured evidence table for Zinc Supplementation, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Zinc SupplementationZinc supplementation in liver cirrhosis: meta-analysis of its effect on biochemical and clinical outcomes.1Gong Y (2026)Zinc supplementation in liver cirrhosis: meta-analysis of its effect on biochemical and clinical outcomes.
Zinc SupplementationZinc-deficient elderly participants received zinc aspartate supplementation for approximately 7 days, resulting in increased serum zinc levels, IFN-γ production, and a trend toward increased ZIP8 expression; in participants taking PPIs, this increase reached statistical significance.4Olah K (2026)Zinc Supplementation Partially Reconstitutes Impaired Interferon-γ Production in the Elderly.
Zinc SupplementationAlthough we found no clear correlation between ZIP8 expression and zinc status, the observed response to supplementation warrants further investigation.4Olah K (2026)Zinc Supplementation Partially Reconstitutes Impaired Interferon-γ Production in the Elderly.
Zinc SupplementationAging impacts immunity, zinc status, and overall health, with these factors being closely interconnected.4Olah K (2026)Zinc Supplementation Partially Reconstitutes Impaired Interferon-γ Production in the Elderly.
Zinc SupplementationZinc is known to modulate protein expression and cytokine production, with new molecular mechanisms continuing to be identified.4Olah K (2026)Zinc Supplementation Partially Reconstitutes Impaired Interferon-γ Production in the Elderly.
topicZinc Supplementation
claimZinc supplementation in liver cirrhosis: meta-analysis of its effect on biochemical and clinical outcomes.
evidence level1
citationGong Y (2026)
sourceZinc supplementation in liver cirrhosis: meta-analysis of its effect on biochemical and clinical outcomes.
topicZinc Supplementation
claimZinc-deficient elderly participants received zinc aspartate supplementation for approximately 7 days, resulting in increased serum zinc levels, IFN-γ production, and a trend toward increased ZIP8 expression; in participants taking PPIs, this increase reached statistical significance.
evidence level4
citationOlah K (2026)
sourceZinc Supplementation Partially Reconstitutes Impaired Interferon-γ Production in the Elderly.
topicZinc Supplementation
claimAlthough we found no clear correlation between ZIP8 expression and zinc status, the observed response to supplementation warrants further investigation.
evidence level4
citationOlah K (2026)
sourceZinc Supplementation Partially Reconstitutes Impaired Interferon-γ Production in the Elderly.
topicZinc Supplementation
claimAging impacts immunity, zinc status, and overall health, with these factors being closely interconnected.
evidence level4
citationOlah K (2026)
sourceZinc Supplementation Partially Reconstitutes Impaired Interferon-γ Production in the Elderly.
topicZinc Supplementation
claimZinc is known to modulate protein expression and cytokine production, with new molecular mechanisms continuing to be identified.
evidence level4
citationOlah K (2026)
sourceZinc Supplementation Partially Reconstitutes Impaired Interferon-γ Production in the Elderly.

Source documents

  1. Zinc supplementation in liver cirrhosis: meta-analysis of its effect on biochemical and clinical outcomes.
  2. Zinc Supplementation Partially Reconstitutes Impaired Interferon-γ Production in the Elderly.