topicZinc Cold Duration Randomized Trial
claim1 2 3 4 5 6 7 8 9 10 11 12 10 13 14 Immune system aging is a cause of increased morbidity and mortality among older adults.
evidence level4
citationCąkała-Jakimowicz Marta (2026)
sourceA Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review
topicZinc Cold Duration Randomized Trial
claimImmunoaging combined with unfavorable environmental influences and an inappropriate lifestyle (environmental pollution, poor dietary habits, lack of physical activity, occupational stress, etc.) is associated with the development and progression of age-related diseases [].
evidence level4
citationCąkała-Jakimowicz Marta (2026)
sourceA Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review
topicZinc Cold Duration Randomized Trial
claimThe process of cellular aging is associated with the accumulation of DNA damage, telomere shortening, epigenetic drift, loss of proteostasis, mitochondrial dysfunction, and impaired intercellular communication [], leading to persistent cell cycle arrest, morphological, metabolic, and functional abnormalities, and relative resistance to apoptosis [,].
evidence level4
citationCąkała-Jakimowicz Marta (2026)
sourceA Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review
topicZinc Cold Duration Randomized Trial
claimImmunoaging involves the involution of lymphatic organs and senescence of immune cells (immunosenescence).
evidence level4
citationCąkała-Jakimowicz Marta (2026)
sourceA Healthy Lifestyle Can Slow Immune System Aging and Reduce Age-Related Chronic Inflammation: A Narrative Review
topicZinc Cold Duration Randomized Trial
claimBackground Effects of treatments on continuous outcomes are commonly estimated using the mean difference (in units of measurement) or the ratio of means (percentages), each providing a single average effect across the study population.
evidence level4
citationHemilä H (2025)
sourceEstimating quantile treatment effect on the original scale of the outcome variable: a case study of common cold treatments.
topicZinc Cold Duration Randomized Trial
claimQuantile treatment effect (QTE) analysis is more informative as it estimates the effect of treatment across the whole population.
evidence level4
citationHemilä H (2025)
sourceEstimating quantile treatment effect on the original scale of the outcome variable: a case study of common cold treatments.