Structured evidence table for Zinc Cognitive Function Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Zinc Cognitive Function Randomized Trial | 1 2 3 4 1 4 5 6 7 L-carnosine (β-alanyl-L-histidine) is a naturally occurring bioactive dipeptide composed of β-alanine and L-histidine, predominantly found in tissues with high metabolic demands such as skeletal muscle and the central nervous system [,]. | 1 | Hsiao Yung-Fang (2026) | The Effects of Carnosine on Cognitive Function and Mental Health—A Systematic Review and Meta-Analysis |
| Zinc Cognitive Function Randomized Trial | Age-associated declines in muscle carnosine content have been associated with reduced exercise capacity and increased fatigue, whereas reductions in brain carnosine levels have been linked to oxidative damage, protein aggregation, and cognitive impairment in neurodegenerative conditions or aging [,,]. | 1 | Hsiao Yung-Fang (2026) | The Effects of Carnosine on Cognitive Function and Mental Health—A Systematic Review and Meta-Analysis |
| Zinc Cognitive Function Randomized Trial | The goal of this scoping review is to identify research areas for which sufficient evidence warrants a systematic review (SR) and meta-analysis. | 1 | Hsiao Yung-Fang (2026) | The Effects of Carnosine on Cognitive Function and Mental Health—A Systematic Review and Meta-Analysis |
| Zinc Cognitive Function Randomized Trial | Mediated by carnosine synthase, the endogenous synthesis of L-carnosine is rate-limited by the availability of β-alanine [,]. | 1 | Hsiao Yung-Fang (2026) | The Effects of Carnosine on Cognitive Function and Mental Health—A Systematic Review and Meta-Analysis |
| Zinc Cognitive Function Randomized Trial | The fully adjusted model revealed a significant association between the high-quality DAQS group and a reduced risk of cognitive impairment compared to the low-quality DAQS group (0.34 (95% CI: 0.22–0.53), < .0001). | 3 | Xu Dehong (2026) | Association between dietary antioxidant quality score and cognitive function in older adults: A cross-sectional study based on NHANES 2011–2014 |
| Zinc Cognitive Function Randomized Trial | 23 25 [–] 25 29 [–] 26 27 [,] 30 [] 31 [] 28 [] Although direct evidence was previously limited, a growing body of recent literature utilizing the NHANES database has begun to explore this relationship.Our findings align with these recent studies,which consistently report a positive association between composite antioxidant indices and cognitive performance. | 3 | Xu Dehong (2026) | Association between dietary antioxidant quality score and cognitive function in older adults: A cross-sectional study based on NHANES 2011–2014 |
| Zinc Cognitive Function Randomized Trial | Our findings suggest that higher levels of DAQS are associated with a lower likelihood of cognitive impairment in older adults, after controlling for variables such as age, gender, race, education, BMI, PIR, smoking status, alcohol consumption, hypertension, and diabetes. | 3 | Xu Dehong (2026) | Association between dietary antioxidant quality score and cognitive function in older adults: A cross-sectional study based on NHANES 2011–2014 |
| Zinc Cognitive Function Randomized Trial | 1 [] 2 [] Cognitive function pertains to the brain’s capacity to perceive and comprehend objective reality, encompassing various faculties such as language, cognition, focus, and memory. | 3 | Xu Dehong (2026) | Association between dietary antioxidant quality score and cognitive function in older adults: A cross-sectional study based on NHANES 2011–2014 |
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