Structured evidence table for Zeaxanthin-Eye-Fatigue-Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Zeaxanthin-Eye-Fatigue-Meta-Analysis | Major vision-threatening conditions such as glaucoma, cataracts, age-related macular degeneration (AMD), diabetic retinopathy (DR), uveitis, retinal detachment, etc., contribute significantly to functional disability and reduced quality of life [,]. | 4 | De Silva Sandun (2026) | Beneficial Effects of Natural Bioactive Compounds on Eye Health: A Narrative Review |
| Zeaxanthin-Eye-Fatigue-Meta-Analysis | Oxidative stress, chronic inflammation, mitochondrial dysfunction, dysregulated angiogenesis and metabolic imbalance are highly associated with the molecular-level pathogenesis of these ocular diseases. | 4 | De Silva Sandun (2026) | Beneficial Effects of Natural Bioactive Compounds on Eye Health: A Narrative Review |
| Zeaxanthin-Eye-Fatigue-Meta-Analysis | Furthermore, bioavailability and therapeutic potential are increased by synergistic interactions among bioactives in whole extracts and improvements in delivery systems (e.g., nano-formulations). | 4 | De Silva Sandun (2026) | Beneficial Effects of Natural Bioactive Compounds on Eye Health: A Narrative Review |
| Zeaxanthin-Eye-Fatigue-Meta-Analysis | 1 2 2 3 4 5 6 Visual impairment is a major global health problem with an increasing prevalence due to population ageing, higher incidence of metabolic diseases such as diabetes, and prolonged exposure to digital devices. | 4 | De Silva Sandun (2026) | Beneficial Effects of Natural Bioactive Compounds on Eye Health: A Narrative Review |
| Zeaxanthin-Eye-Fatigue-Meta-Analysis | 1 2 3 5 6 7 8 9 More than two billion people are at risk of micronutrient deficiencies, which often involve multiple, rather than single, nutrients [,]. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Zeaxanthin-Eye-Fatigue-Meta-Analysis | They are widely used to help individuals meet their daily nutrient requirements, support overall health, and address increased nutritional needs associated with pregnancy, aging, and illness. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Zeaxanthin-Eye-Fatigue-Meta-Analysis | According to the National Health and Nutrition Examination Survey, MVM use in the USA increased from 35% in 1999-2000 [] to 49-52% between 2011 and 2014, with higher usage among women than men [-]. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
| Zeaxanthin-Eye-Fatigue-Meta-Analysis | The most common deficiencies include vitamin A, folic acid, vitamin D, iron, iodine, and zinc, especially among children and women in low- and middle-income countries [-]. | 4 | Muacevic Alexander (2026) | A to Z of Health: An Evidence-Based Narrative Review of Multivitamin-Multimineral and Nutraceutical Supplementation |
Source documents