topicVitamin E Muscle Soreness Randomized Trial
claimOnly in 3 of the 14 studies was muscle soreness found to be significantly reduced in response to vitamin C and/or vitamin E supplementation at all time points when compared to the placebo group.
evidence level1
citationTorre MF (2021)
sourceSupplementation with Vitamins C and E and Exercise-Induced Delayed-Onset Muscle Soreness: A Systematic Review.
topicVitamin E Muscle Soreness Randomized Trial
claimDespite some studies showing the beneficial effects of chronic supplementation with these vitamins on muscle soreness manifesting 24-72 h after eccentric exercise, the evidence is so far insufficient to confirm that the intake of antioxidant vitamins is able to minimize delayed-onset muscle soreness in this context.
evidence level1
citationTorre MF (2021)
sourceSupplementation with Vitamins C and E and Exercise-Induced Delayed-Onset Muscle Soreness: A Systematic Review.
topicVitamin E Muscle Soreness Randomized Trial
claimMuscle damage induced by exercise may have several consequences such as delayed-onset muscle soreness, a side-effect of the release of free radicals during oxidative stress.
evidence level1
citationTorre MF (2021)
sourceSupplementation with Vitamins C and E and Exercise-Induced Delayed-Onset Muscle Soreness: A Systematic Review.
topicVitamin E Muscle Soreness Randomized Trial
claimTo mitigate the oxidative stress cascade, the oral intake of antioxidants has been assessed by several research groups.
evidence level1
citationTorre MF (2021)
sourceSupplementation with Vitamins C and E and Exercise-Induced Delayed-Onset Muscle Soreness: A Systematic Review.
topicVitamin E Muscle Soreness Randomized Trial
claim1 2 3 4 5 6 7 8 9 Physical activity guidelines recommend that muscle strengthening exercises are performed on at least 2 days per week (), with the consensus that resistance exercise is the most efficacious way to increase muscle mass and strength, alongside broad ranging health benefits including lowering risk of premature mortality (,).
evidence level2
citationLithgow Hannah (2026)
sourceThe effects of vitamin K 2 on recovery from muscle damaging resistance exercise in young and older adults – The TAKEOVER randomised controlled trial
topicVitamin E Muscle Soreness Randomized Trial
claimThis is particularly important in older adults as resistance exercise can reduce injury risk, including risk of falls and fractures, and subsequently promote longevity by supporting healthy ageing ().
evidence level2
citationLithgow Hannah (2026)
sourceThe effects of vitamin K 2 on recovery from muscle damaging resistance exercise in young and older adults – The TAKEOVER randomised controlled trial
topicVitamin E Muscle Soreness Randomized Trial
claimThe consequences of EIMD include a temporary loss of muscular function, experiencing muscle soreness and pain, reduced muscle force production, and an increase in inflammation ().
evidence level2
citationLithgow Hannah (2026)
sourceThe effects of vitamin K 2 on recovery from muscle damaging resistance exercise in young and older adults – The TAKEOVER randomised controlled trial