Vitamin D2 Vs D3 Evidence Table

Structured evidence table for Vitamin D2 Vs D3, generated from 3 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Vitamin D2 Vs D3Apart from causing bone diseases such as osteomalacia and rickets, vitamin D deficiency has been associated with an increased risk of multiple conditions, including cancer, kidney disease, cardiovascular issues, multiple sclerosis, and autoimmune diseases.4Chen Xiaohong (2026)Potential insufficiency of vitamin D in healthy individuals: divergent performances of C3-epi-D3 levels and percentages
Vitamin D2 Vs D3These health issues are often linked to oxidative stress or immune dysfunction associated with vitamin D deficiency.4Chen Xiaohong (2026)Potential insufficiency of vitamin D in healthy individuals: divergent performances of C3-epi-D3 levels and percentages
Vitamin D2 Vs D3Therefore, it is necessary to accurately evaluate in vivo vitamin D levels to offer evidence for vitamin D supplementation, thereby addressing deficiencies and mitigating disease risks.4Chen Xiaohong (2026)Potential insufficiency of vitamin D in healthy individuals: divergent performances of C3-epi-D3 levels and percentages
Vitamin D2 Vs D31 2 3 4 , Vitamin D deficiency is prevalent in both developed and developing countries worldwide.4Chen Xiaohong (2026)Potential insufficiency of vitamin D in healthy individuals: divergent performances of C3-epi-D3 levels and percentages
Vitamin D2 Vs D3Objective Vitamin D(VitD) deficiency has been found prevalent among patients with thyroid autoimmunity (TAI).4Luo D (2025)The development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.
Vitamin D2 Vs D3Results The serum levels of VitD and VitD3 were pronouncedly lower in the male euthyroid subjects with TAI (n = 195) than those non-TAI men (n = 2687, P Conclusion Based on the cross-sectional and prospective investigations, our findings further indicate that VDD may be an independent risk factor for TAI development.4Luo D (2025)The development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.
Vitamin D2 Vs D3Moreover, the latter is potentially associated with the deficiency of VitD3 rather than VitD2 in the euthyroid male population although the related mechanisms await in-depth exploration.4Luo D (2025)The development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.
Vitamin D2 Vs D3This study aimed to investigate whether low VitD2 or VitD3 potentially contributed to the development of TAI in euthyroid male patients, which had not been reported before.4Luo D (2025)The development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.
Vitamin D2 Vs D3Vitamin D deficiency and metabolism disorders are also common, resulting from impaired conversion of 25(OH)D3 to its active form, 1,25(OH)2D3, and reduced inactivation to 24,25(OH)2D3.4Hryciuk M (2025)Assessment of Vitamin D Metabolism Disorders in Hemodialysis Patients.
Vitamin D2 Vs D3Background Patients with end-stage chronic diseases, especially those undergoing hemodialysis (HD), often experience mineral bone disease (MBD), leading to hypocalcemia, hyperphosphatemia, and elevated parathyroid hormone (PTH).4Hryciuk M (2025)Assessment of Vitamin D Metabolism Disorders in Hemodialysis Patients.
topicVitamin D2 Vs D3
claimApart from causing bone diseases such as osteomalacia and rickets, vitamin D deficiency has been associated with an increased risk of multiple conditions, including cancer, kidney disease, cardiovascular issues, multiple sclerosis, and autoimmune diseases.
evidence level4
citationChen Xiaohong (2026)
sourcePotential insufficiency of vitamin D in healthy individuals: divergent performances of C3-epi-D3 levels and percentages
topicVitamin D2 Vs D3
claimThese health issues are often linked to oxidative stress or immune dysfunction associated with vitamin D deficiency.
evidence level4
citationChen Xiaohong (2026)
sourcePotential insufficiency of vitamin D in healthy individuals: divergent performances of C3-epi-D3 levels and percentages
topicVitamin D2 Vs D3
claimTherefore, it is necessary to accurately evaluate in vivo vitamin D levels to offer evidence for vitamin D supplementation, thereby addressing deficiencies and mitigating disease risks.
evidence level4
citationChen Xiaohong (2026)
sourcePotential insufficiency of vitamin D in healthy individuals: divergent performances of C3-epi-D3 levels and percentages
topicVitamin D2 Vs D3
claim1 2 3 4 , Vitamin D deficiency is prevalent in both developed and developing countries worldwide.
evidence level4
citationChen Xiaohong (2026)
sourcePotential insufficiency of vitamin D in healthy individuals: divergent performances of C3-epi-D3 levels and percentages
topicVitamin D2 Vs D3
claimObjective Vitamin D(VitD) deficiency has been found prevalent among patients with thyroid autoimmunity (TAI).
evidence level4
citationLuo D (2025)
sourceThe development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.
topicVitamin D2 Vs D3
claimResults The serum levels of VitD and VitD3 were pronouncedly lower in the male euthyroid subjects with TAI (n = 195) than those non-TAI men (n = 2687, P Conclusion Based on the cross-sectional and prospective investigations, our findings further indicate that VDD may be an independent risk factor for TAI development.
evidence level4
citationLuo D (2025)
sourceThe development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.
topicVitamin D2 Vs D3
claimMoreover, the latter is potentially associated with the deficiency of VitD3 rather than VitD2 in the euthyroid male population although the related mechanisms await in-depth exploration.
evidence level4
citationLuo D (2025)
sourceThe development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.
topicVitamin D2 Vs D3
claimThis study aimed to investigate whether low VitD2 or VitD3 potentially contributed to the development of TAI in euthyroid male patients, which had not been reported before.
evidence level4
citationLuo D (2025)
sourceThe development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.
topicVitamin D2 Vs D3
claimVitamin D deficiency and metabolism disorders are also common, resulting from impaired conversion of 25(OH)D3 to its active form, 1,25(OH)2D3, and reduced inactivation to 24,25(OH)2D3.
evidence level4
citationHryciuk M (2025)
sourceAssessment of Vitamin D Metabolism Disorders in Hemodialysis Patients.
topicVitamin D2 Vs D3
claimBackground Patients with end-stage chronic diseases, especially those undergoing hemodialysis (HD), often experience mineral bone disease (MBD), leading to hypocalcemia, hyperphosphatemia, and elevated parathyroid hormone (PTH).
evidence level4
citationHryciuk M (2025)
sourceAssessment of Vitamin D Metabolism Disorders in Hemodialysis Patients.

Source documents

  1. Potential insufficiency of vitamin D in healthy individuals: divergent performances of C3-epi-D3 levels and percentages
  2. The development of thyroid autoimmunity is potentially associated with the deficiency of vitamin D3 rather than vitamin D2 in euthyroid men.
  3. Assessment of Vitamin D Metabolism Disorders in Hemodialysis Patients.