topicValerian Insomnia Meta-Analysis
claimThese nocturnal difficulties are frequently accompanied by pronounced daytime impairments that impede optimal functioning, including fatigue, mood instability, and reduced concentration.
evidence level3
citationYang Shurui (2026)
sourceValeriana species and insomnia: multi-organ mechanisms and translational perspectives
topicValerian Insomnia Meta-Analysis
claimInsomnia can present as a standalone condition or co-occur with other medical and mental health disorders, posing a risk for their progression or exacerbation if untreated (Perlis et al.; Riemann et al.).
evidence level3
citationYang Shurui (2026)
sourceValeriana species and insomnia: multi-organ mechanisms and translational perspectives
topicValerian Insomnia Meta-Analysis
claimAlthough some medications are effective for treating acute insomnia, many approved options, including benzodiazepines, zaleplon, zolpidem, and eszopiclone, are associated with poor tolerability and limited data regarding their long-term effects (De Crescenzo et al.).
evidence level3
citationYang Shurui (2026)
sourceValeriana species and insomnia: multi-organ mechanisms and translational perspectives
topicValerian Insomnia Meta-Analysis
claim2023 2022 2022 2022 2022 2022 2022 2022 The increasing prevalence of insomnia among adults, particularly in aging populations, is significantly diminishing quality of life.
evidence level3
citationYang Shurui (2026)
sourceValeriana species and insomnia: multi-organ mechanisms and translational perspectives
topicValerian Insomnia Meta-Analysis
claimFailure to meet the recommended 7-9 hours of restful sleep per night is known to increase the risk of several health conditions, reason why regular and adequate sleep should be seen as a priority instead of an unnecessary commodity easily traded as required by the commitments of our busy lives.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicValerian Insomnia Meta-Analysis
claimWhile both the quantity and the quality of sleep can be largely improved with relatively straightforward practices dictated by good sleep hygiene, emerging research suggests that dietary and supplementation protocols focused on certain foods, nutrients, and biochemical compounds with sleep-promoting properties can act as subsidiary sleep aids in complementing these behavioral changes.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicValerian Insomnia Meta-Analysis
claimThe scope of this narrative review is to summarize the available evidence on the potential benefits of selected nutraceuticals in the context of circadian rhythm and sleep disturbances, namely melatonin, magnesium, omega-3 fatty acids, tart cherry juice, kiwifruit, apigenin, valerian root, L-theanine, glycine, ashwagandha, myoinositol, Rhodiola rosea, and phosphatidylserine.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.
topicValerian Insomnia Meta-Analysis
claimHumans spend approximately one third of their life asleep but, as counterintuitive as it may sound, sleep is far from being a quiet state of inactivity.
evidence level4
citationConti F (2026)
sourceDietary Protocols to Promote and Improve Restful Sleep: A Narrative Review.