topicUrolithin A Exercise Recovery Meta-Analysis
claimImportantly, these biological changes manifest most meaningfully through declines in functional capacity, including reduced muscle strength, impaired metabolic regulation, diminished cognitive performance, and increased disease risk.
evidence level4
citationKurtz Jennifer A. (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits
topicUrolithin A Exercise Recovery Meta-Analysis
claimThis article aims to synthesize evidence from human studies evaluating dietary supplements that directly or indirectly modulate the recognized hallmarks of aging, such as mitochondrial dysfunction, oxidative stress, inflammation, and proteostasis.
evidence level4
citationKurtz Jennifer A. (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits
topicUrolithin A Exercise Recovery Meta-Analysis
claimRather than providing an exhaustive account of all supplements ever studied, this review focuses on representative compounds with the strongest or most emerging human evidence.
evidence level4
citationKurtz Jennifer A. (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits
topicUrolithin A Exercise Recovery Meta-Analysis
claimAging is a complex, multifaceted process marked by a gradual decline in physiological.
evidence level4
citationKurtz Jennifer A. (2026)
sourceTargeted Supplementation and Nutritional Strategies for Healthy Aging: A Review of Physiological and Molecular Benefits
topicUrolithin A Exercise Recovery Meta-Analysis
claimWukich and colleagues established that diabetes adversely affects outcomes across all orthopedic subspecialties, including increased surgical site infections, delayed wound healing, and impaired bone consolidation [].
evidence level4
citationSantos Márcia da Silva (2026)
sourceNutritional Interventions to Optimize Orthobiologic Therapy Quality in Type 2 Diabetes Mellitus: Molecular Mechanisms and Clinical Framework: A Narrative Review
topicUrolithin A Exercise Recovery Meta-Analysis
claimMeta-analytic evidence demonstrates that diabetic patients have an odds ratio of 2.11 for impaired fracture healing compared to non-diabetic individuals [], while tendinopathy prevalence is markedly elevated, with 27.5% of diabetic patients experiencing shoulder disorders compared to 5% in the general population [,].
evidence level4
citationSantos Márcia da Silva (2026)
sourceNutritional Interventions to Optimize Orthobiologic Therapy Quality in Type 2 Diabetes Mellitus: Molecular Mechanisms and Clinical Framework: A Narrative Review
topicUrolithin A Exercise Recovery Meta-Analysis
claimA notable 19-year follow-up study confirmed a persistent increased risk of tendon injury in patients with structured diabetes care.
evidence level4
citationSantos Márcia da Silva (2026)
sourceNutritional Interventions to Optimize Orthobiologic Therapy Quality in Type 2 Diabetes Mellitus: Molecular Mechanisms and Clinical Framework: A Narrative Review
topicUrolithin A Exercise Recovery Meta-Analysis
claim1 2 3 4 Type 2 diabetes mellitus (T2DM) has reached pandemic proportions, affecting over 537 million adults globally, with projections indicating 783 million by 2045 [].
evidence level4
citationSantos Márcia da Silva (2026)
sourceNutritional Interventions to Optimize Orthobiologic Therapy Quality in Type 2 Diabetes Mellitus: Molecular Mechanisms and Clinical Framework: A Narrative Review