topicTryptophan Sleep Quality Randomized Trial
claimThis meta-analysis's results suggest dietary interventions significantly improved sleep outcomes: reduced PSQI (MD: -0.70, 95% CI: -1.37 to -0.03, p p p p p = 0.05).
evidence level1
citationMei M (2025)
sourceDietary Supplement Interventions and Sleep Quality Improvement: A Systematic Review and Meta-Analysis.
topicTryptophan Sleep Quality Randomized Trial
claimBackground/objectives Sleep health impacts numerous domains of human health, and sleep deprivation has emerged as a significant public health concern.
evidence level1
citationMei M (2025)
sourceDietary Supplement Interventions and Sleep Quality Improvement: A Systematic Review and Meta-Analysis.
topicTryptophan Sleep Quality Randomized Trial
claimMultiple types of dietary nutrient supplementation, dietary intake, and the use of nutritional supplements to enhance sleep quality are recognized as effective methods to improve sleep quality.
evidence level1
citationMei M (2025)
sourceDietary Supplement Interventions and Sleep Quality Improvement: A Systematic Review and Meta-Analysis.
topicTryptophan Sleep Quality Randomized Trial
claimThis internal clock synchronizes with external environmental cues, primarily light, but emerging evidence suggests that food intake patterns also serve as important zeitgebers (time‐givers) (Cedernaes et al. ).
evidence level3
citationAbou‐Khalil Rony (2025)
sourceNutritional Interventions for Enhancing Sleep Quality: The Role of Diet and Key Nutrients in Regulating Sleep Patterns and Disorders
topicTryptophan Sleep Quality Randomized Trial
claim2025 2017 2017 2012 1998 Micronutrients such as magnesium, zinc, and iron are critical for neurotransmitter regulation and have been associated with improvements in sleep quality and reductions in nocturnal awakenings (Zhang et al. ; Cherasse and Urade ; Gholipour Baradari et al. ; Abbasi et al. ).
evidence level3
citationAbou‐Khalil Rony (2025)
sourceNutritional Interventions for Enhancing Sleep Quality: The Role of Diet and Key Nutrients in Regulating Sleep Patterns and Disorders
topicTryptophan Sleep Quality Randomized Trial
claimSimilarly, polyphenols—especially flavonoids found in fruits, vegetables, and teas—exhibit antioxidative and anti‐inflammatory properties that may modulate sleep by influencing GABAergic pathways and reducing neuroinflammation (Bravo ).
evidence level3
citationAbou‐Khalil Rony (2025)
sourceNutritional Interventions for Enhancing Sleep Quality: The Role of Diet and Key Nutrients in Regulating Sleep Patterns and Disorders
topicTryptophan Sleep Quality Randomized Trial
claim2015 Sleep is a fundamental biological process essential for maintaining optimal physical, emotional, and cognitive health.
evidence level3
citationAbou‐Khalil Rony (2025)
sourceNutritional Interventions for Enhancing Sleep Quality: The Role of Diet and Key Nutrients in Regulating Sleep Patterns and Disorders