Structured evidence table for Tocotrienols Cholesterol Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Tocotrienols Cholesterol Meta-Analysis | Hyperlipidemia, characterized by elevated lipid levels, is a major risk factor for cardiovascular diseases (CVD), including atherosclerosis. | 1 | Abdah HW (2025) | Effect of tocotrienol-rich fraction (TRF) on lipid profile in hyperlipidemic experimental animal model: a systematic review and meta-analysis. |
| Tocotrienols Cholesterol Meta-Analysis | TRF significantly reduced total cholesterol (effect size = - 4.675, p < 0.0001), LDL (- 4.847, p < 0.0001), and triglycerides (- 4.736, p < 0.0001), while significantly increasing HDL (4.001, p < 0.0001), particularly in rats and mice. | 1 | Abdah HW (2025) | Effect of tocotrienol-rich fraction (TRF) on lipid profile in hyperlipidemic experimental animal model: a systematic review and meta-analysis. |
| Tocotrienols Cholesterol Meta-Analysis | Tocotrienol-rich fraction (TRF), a potent form of vitamin E, has demonstrated promising lipid-lowering effects due to its antioxidant and anti-inflammatory properties. | 1 | Abdah HW (2025) | Effect of tocotrienol-rich fraction (TRF) on lipid profile in hyperlipidemic experimental animal model: a systematic review and meta-analysis. |
| Tocotrienols Cholesterol Meta-Analysis | Moreover, changes in blood markers associated with inflammation, oxidative stress, and neurotropic activity were examined. | 2 | Lopresti AL (2025) | An examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial. |
| Tocotrienols Cholesterol Meta-Analysis | Results Compared to the placebo, tocotrienol supplementation was associated with greater improvements in general memory ( p = 0.045, 95% CI: 0.34, 32.21). | 2 | Lopresti AL (2025) | An examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial. |
| Tocotrienols Cholesterol Meta-Analysis | Conclusion This is the first controlled study demonstrating the cognitive-enhancing and sleep-promoting effects of stand-alone supplementation with tocotrienols. | 2 | Lopresti AL (2025) | An examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial. |
| Tocotrienols Cholesterol Meta-Analysis | Background/objectives Tocotrienols are a form of vitamin E that may have neuroprotective effects. | 2 | Lopresti AL (2025) | An examination into the effects of tocotrienols (TheraPrimE® rice) on cognitive abilities and sleep in healthy adults: a randomised, double-blind, placebo-controlled trial. |
Source documents