topicSpirulina Lipids Meta-Analysis
claimAlgae supplementation showed a suggestive improvement in VO 2 max (SMD = 0.88, 95% CI: 0.00-1.75) and significantly improved in TTE (SMD = 1.06, 95% CI: 0.16-1.96), with smaller effects on WRmax (SMD = 0.29, 95% CI: 0.03-0.55), and no significant benefit for TT performance (SMD = -0.27, 95% CI: -0.74 to 0.21).
evidence level1
citationWei Y (2026)
sourceThe Effects of Seaweed and Microalgae Supplementation on Exercise Performance and Recovery: A Systematic Review and Meta-Analysis.
topicSpirulina Lipids Meta-Analysis
claimRegarding recovery, CK concentrations were significantly reduced (SMD = -0.78, 95% CI: -1.28 to -0.28).
evidence level1
citationWei Y (2026)
sourceThe Effects of Seaweed and Microalgae Supplementation on Exercise Performance and Recovery: A Systematic Review and Meta-Analysis.
topicSpirulina Lipids Meta-Analysis
claimSensitivity analyses supported the robustness of the main findings with minimal evidence of publication bias.
evidence level1
citationWei Y (2026)
sourceThe Effects of Seaweed and Microalgae Supplementation on Exercise Performance and Recovery: A Systematic Review and Meta-Analysis.
topicSpirulina Lipids Meta-Analysis
claimObjective: Seaweed and microalgae provide antioxidants, polyunsaturated fatty acids, and bioactive compounds that may enhance exercise performance and accelerate recovery.
evidence level1
citationWei Y (2026)
sourceThe Effects of Seaweed and Microalgae Supplementation on Exercise Performance and Recovery: A Systematic Review and Meta-Analysis.
topicSpirulina Lipids Meta-Analysis
claimChlorella 5 7 8 9 10 Emerging evidence suggests that supplementation withand spirulina may be associated with improvements in metabolic parameters such as insulin sensitivity, lipid profiles, and hepatic steatosis markers while simultaneously reducing systemic inflammatory burden and oxidative stress.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Lipids Meta-Analysis
claimWe also discuss clinical evidence, safety considerations, and translational perspectives, highlighting current knowledge gaps and future research directions necessary for the rational development of microalgae-based interventions in preventive and integrative medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Lipids Meta-Analysis
claim2 7 19 In spirulina, phycobiliproteins, particularly phycocyanin, are the dominant pigment-derived bioactives, with documented antioxidant and anti-inflammatory activity and emerging evidence for metabolic signaling effects including Nrf2 activation and the attenuation of oxidative stress in preclinical models [,,].
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Lipids Meta-Analysis
claimChlorella Arthrospira Microalgae represent a diverse group of aquatic photosynthetic microorganisms and a rich source of bioactive compounds with significant potential in functional foods, nutraceuticals, and preventive medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence