Spirulina Cholesterol Meta-Analysis Evidence Table

Structured evidence table for Spirulina Cholesterol Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Spirulina Cholesterol Meta-Analysis1 2 3 4 2 2 2 Obesity constitutes a major global health concern, closely associated with a range of metabolic dysfunctions such as insulin resistance, dyslipidemia, and chronic systemic inflammation.1Yasul Yavuz (2026)Combined Role of Spirulina and Exercise-Based Interventions in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis
Spirulina Cholesterol Meta-AnalysisThese dysfunctions significantly elevate the risk of developing type 2 diabetes, cardiovascular disease, and other metabolic syndromes, underscoring the need for comprehensive and integrative interventions [,].1Yasul Yavuz (2026)Combined Role of Spirulina and Exercise-Based Interventions in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis
Spirulina Cholesterol Meta-AnalysisAccording to the World Health Organization (WHO), individuals with a body mass index (BMI) ≥ 25 kg/m, encompassing both overweight (25.0–29.9 kg/m) and obese (≥30.0 kg/m) categories, are at increased cardiometabolic risk and were therefore included in this systematic review.1Yasul Yavuz (2026)Combined Role of Spirulina and Exercise-Based Interventions in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis
Spirulina Cholesterol Meta-AnalysisChlorella 5 7 8 9 10 Emerging evidence suggests that supplementation withand spirulina may be associated with improvements in metabolic parameters such as insulin sensitivity, lipid profiles, and hepatic steatosis markers while simultaneously reducing systemic inflammatory burden and oxidative stress.3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
Spirulina Cholesterol Meta-AnalysisWe also discuss clinical evidence, safety considerations, and translational perspectives, highlighting current knowledge gaps and future research directions necessary for the rational development of microalgae-based interventions in preventive and integrative medicine.3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
Spirulina Cholesterol Meta-Analysis2 7 19 In spirulina, phycobiliproteins, particularly phycocyanin, are the dominant pigment-derived bioactives, with documented antioxidant and anti-inflammatory activity and emerging evidence for metabolic signaling effects including Nrf2 activation and the attenuation of oxidative stress in preclinical models [,,].3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
Spirulina Cholesterol Meta-AnalysisChlorella Arthrospira Microalgae represent a diverse group of aquatic photosynthetic microorganisms and a rich source of bioactive compounds with significant potential in functional foods, nutraceuticals, and preventive medicine.3Rzeski Wojciech (2026)Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Cholesterol Meta-Analysis
claim1 2 3 4 2 2 2 Obesity constitutes a major global health concern, closely associated with a range of metabolic dysfunctions such as insulin resistance, dyslipidemia, and chronic systemic inflammation.
evidence level1
citationYasul Yavuz (2026)
sourceCombined Role of Spirulina and Exercise-Based Interventions in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis
topicSpirulina Cholesterol Meta-Analysis
claimThese dysfunctions significantly elevate the risk of developing type 2 diabetes, cardiovascular disease, and other metabolic syndromes, underscoring the need for comprehensive and integrative interventions [,].
evidence level1
citationYasul Yavuz (2026)
sourceCombined Role of Spirulina and Exercise-Based Interventions in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis
topicSpirulina Cholesterol Meta-Analysis
claimAccording to the World Health Organization (WHO), individuals with a body mass index (BMI) ≥ 25 kg/m, encompassing both overweight (25.0–29.9 kg/m) and obese (≥30.0 kg/m) categories, are at increased cardiometabolic risk and were therefore included in this systematic review.
evidence level1
citationYasul Yavuz (2026)
sourceCombined Role of Spirulina and Exercise-Based Interventions in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis
topicSpirulina Cholesterol Meta-Analysis
claimChlorella 5 7 8 9 10 Emerging evidence suggests that supplementation withand spirulina may be associated with improvements in metabolic parameters such as insulin sensitivity, lipid profiles, and hepatic steatosis markers while simultaneously reducing systemic inflammatory burden and oxidative stress.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Cholesterol Meta-Analysis
claimWe also discuss clinical evidence, safety considerations, and translational perspectives, highlighting current knowledge gaps and future research directions necessary for the rational development of microalgae-based interventions in preventive and integrative medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Cholesterol Meta-Analysis
claim2 7 19 In spirulina, phycobiliproteins, particularly phycocyanin, are the dominant pigment-derived bioactives, with documented antioxidant and anti-inflammatory activity and emerging evidence for metabolic signaling effects including Nrf2 activation and the attenuation of oxidative stress in preclinical models [,,].
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
topicSpirulina Cholesterol Meta-Analysis
claimChlorella Arthrospira Microalgae represent a diverse group of aquatic photosynthetic microorganisms and a rich source of bioactive compounds with significant potential in functional foods, nutraceuticals, and preventive medicine.
evidence level3
citationRzeski Wojciech (2026)
sourceChlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence

Source documents

  1. Combined Role of Spirulina and Exercise-Based Interventions in Individuals with Overweight and Obesity: A Systematic Review and Meta-Analysis
  2. Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence