topicSodium Exercise Performance Randomized Trial
claimThe Effects of Combined Caffeine and Sodium Bicarbonate Supplementation on Exercise Performance, Physiological Responses, and Gastrointestinal Tolerability: A Systematic Review and Meta-Analysis
evidence level1
citationChen X (2026)
sourceThe Effects of Combined Caffeine and Sodium Bicarbonate Supplementation on Exercise Performance, Physiological Responses, and Gastrointestinal Tolerability: A Systematic Review and Meta-Analysis
topicSodium Exercise Performance Randomized Trial
claimHowever, comparisons among active conditions provided no clear evidence that co-ingestion was superior to either supplement alone.
evidence level1
citationLiu S (2026)
sourceIndividual and Combined Effects of Acute Caffeine and Sodium Bicarbonate Supplementation on Exercise Performance and Metabolic Responses: A Bayesian Network Meta-Analysis of Co-Supplementation Trials.
topicSodium Exercise Performance Randomized Trial
claimSB increased blood pH (g = 0.95) and blood lactate (g = 1.13), whereas caffeine reduced blood bicarbonate (g = -0.89).
evidence level1
citationLiu S (2026)
sourceIndividual and Combined Effects of Acute Caffeine and Sodium Bicarbonate Supplementation on Exercise Performance and Metabolic Responses: A Bayesian Network Meta-Analysis of Co-Supplementation Trials.
topicSodium Exercise Performance Randomized Trial
claimBackground : Caffeine and sodium bicarbonate (SB) are widely used ergogenic supplements that influence exercise performance through distinct physiological mechanisms and may differentially modulate exercise-related metabolic responses.
evidence level1
citationLiu S (2026)
sourceIndividual and Combined Effects of Acute Caffeine and Sodium Bicarbonate Supplementation on Exercise Performance and Metabolic Responses: A Bayesian Network Meta-Analysis of Co-Supplementation Trials.
topicSodium Exercise Performance Randomized Trial
claimWhether their co-ingestion provides benefits beyond either supplement alone remains uncertain.
evidence level1
citationLiu S (2026)
sourceIndividual and Combined Effects of Acute Caffeine and Sodium Bicarbonate Supplementation on Exercise Performance and Metabolic Responses: A Bayesian Network Meta-Analysis of Co-Supplementation Trials.