Sesame Lignans Cholesterol Randomized Trial Evidence Table

Structured evidence table for Sesame Lignans Cholesterol Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Sesame Lignans Cholesterol Randomized TrialThe harvested area (which has expanded from 5.0 million hectares in 1961 to 13.97 million ha in 2022) and the production of sesame have increased over the last few decades (1.4 million tonnes in 1961 to 7.4 million tonnes in 2022) [,].3Mostashari Parisa (2024)Sesame Seeds: A Nutrient-Rich Superfood
Sesame Lignans Cholesterol Randomized TrialAccording to Ahmad and Ghosh’s (2020) research, sesame seeds possess a high nutrient content that may benefit the immune system significantly and potentially mitigate the risk of health complications associated with COVID-19.3Mostashari Parisa (2024)Sesame Seeds: A Nutrient-Rich Superfood
Sesame Lignans Cholesterol Randomized TrialHsu and Parthasarathy [] have indicated that the consumption of sesame oil can reduce levels of low-density lipoprotein (LDL) and decrease the risk of atherosclerosis and cardiovascular diseases.3Mostashari Parisa (2024)Sesame Seeds: A Nutrient-Rich Superfood
Sesame Lignans Cholesterol Randomized TrialSesamum indicum ajonjoli hu ma gergelim goma sesame til konjed 1 2 3 4 5 5 6 7 8 7 9 7 8 10 11 12 13 14 15 Sesame (L.) is a plant classified under the Pedaliaceae family and is often called the “seed of immortality.” This plant is an erect annual herb that has different names across various cultures, including(Spanish),(Chinese),(Portuguese),(Japanese),(French),(Hindi), and(Persian) [,,].3Mostashari Parisa (2024)Sesame Seeds: A Nutrient-Rich Superfood
Sesame Lignans Cholesterol Randomized TrialFurthermore, sesamin significantly reduced the levels of 24S-hydroxycholesterol in rat plasma and brain tissues, and down-regulated the protein expressions of CYP46A1, NMDAR2A, NMDAR2B, and HMGCR.4Du J (2022)Characterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity.
Sesame Lignans Cholesterol Randomized TrialInhibition of CYP46A1 activity serves as a therapeutic target for excitatory neurotoxicity.4Du J (2022)Characterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity.
Sesame Lignans Cholesterol Randomized TrialSesame is a common medicine and food resource; its component lignans possess various pharmacological activities.4Du J (2022)Characterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity.
topicSesame Lignans Cholesterol Randomized Trial
claimThe harvested area (which has expanded from 5.0 million hectares in 1961 to 13.97 million ha in 2022) and the production of sesame have increased over the last few decades (1.4 million tonnes in 1961 to 7.4 million tonnes in 2022) [,].
evidence level3
citationMostashari Parisa (2024)
sourceSesame Seeds: A Nutrient-Rich Superfood
topicSesame Lignans Cholesterol Randomized Trial
claimAccording to Ahmad and Ghosh’s (2020) research, sesame seeds possess a high nutrient content that may benefit the immune system significantly and potentially mitigate the risk of health complications associated with COVID-19.
evidence level3
citationMostashari Parisa (2024)
sourceSesame Seeds: A Nutrient-Rich Superfood
topicSesame Lignans Cholesterol Randomized Trial
claimHsu and Parthasarathy [] have indicated that the consumption of sesame oil can reduce levels of low-density lipoprotein (LDL) and decrease the risk of atherosclerosis and cardiovascular diseases.
evidence level3
citationMostashari Parisa (2024)
sourceSesame Seeds: A Nutrient-Rich Superfood
topicSesame Lignans Cholesterol Randomized Trial
claimSesamum indicum ajonjoli hu ma gergelim goma sesame til konjed 1 2 3 4 5 5 6 7 8 7 9 7 8 10 11 12 13 14 15 Sesame (L.) is a plant classified under the Pedaliaceae family and is often called the “seed of immortality.” This plant is an erect annual herb that has different names across various cultures, including(Spanish),(Chinese),(Portuguese),(Japanese),(French),(Hindi), and(Persian) [,,].
evidence level3
citationMostashari Parisa (2024)
sourceSesame Seeds: A Nutrient-Rich Superfood
topicSesame Lignans Cholesterol Randomized Trial
claimFurthermore, sesamin significantly reduced the levels of 24S-hydroxycholesterol in rat plasma and brain tissues, and down-regulated the protein expressions of CYP46A1, NMDAR2A, NMDAR2B, and HMGCR.
evidence level4
citationDu J (2022)
sourceCharacterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity.
topicSesame Lignans Cholesterol Randomized Trial
claimInhibition of CYP46A1 activity serves as a therapeutic target for excitatory neurotoxicity.
evidence level4
citationDu J (2022)
sourceCharacterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity.
topicSesame Lignans Cholesterol Randomized Trial
claimSesame is a common medicine and food resource; its component lignans possess various pharmacological activities.
evidence level4
citationDu J (2022)
sourceCharacterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity.

Source documents

  1. Sesame Seeds: A Nutrient-Rich Superfood
  2. Characterization of three naturally occurring lignans, sesamol, sesamolin, and sesamin, as potent inhibitors of human cytochrome P450 46A1: Implications for treating excitatory neurotoxicity.