evidence table
Selenium Thyroid Autoimmunity Meta-Analysis Evidence Table
Structured evidence table for Selenium Thyroid Autoimmunity Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Selenium Thyroid Autoimmunity Meta-Analysis | Combination therapy significantly reduced TSH levels compared with Sel monotherapy (SMD -1.26; 95% CI -1.51 to -1.00; p 2 = 0%), and TSA suggested that this finding may be robust, although the evidence is limited by the small number of studies. | 1 | Stanchev P (2026) | Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto's Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis. |
| Selenium Thyroid Autoimmunity Meta-Analysis | TgAb levels were also significantly reduced (SMD -0.51; 95% CI -0.78 to -0.24; p 2 = 0%); however, TSA indicated a potential risk of type I error. | 1 | Stanchev P (2026) | Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto's Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis. |
| Selenium Thyroid Autoimmunity Meta-Analysis | Conclusions : MI combined with Sel was associated with a significant reduction in TSH levels compared with Sel alone in patients with HT and subclinical hypothyroidism, suggesting a potential therapeutic benefit. | 1 | Stanchev P (2026) | Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto's Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis. |
| Selenium Thyroid Autoimmunity Meta-Analysis | Introduction : Hashimoto's thyroiditis (HT) is the leading cause of hypothyroidism in iodine-sufficient regions and often presents with subclinical hypothyroidism. | 1 | Stanchev P (2026) | Myo-Inositol Plus Selenium vs. Selenium Alone in Hashimoto's Thyroiditis with Subclinical Hypothyroidism: A Systematic Review and Updated Meta-Analysis with Trial Sequential Analysis. |
| Selenium Thyroid Autoimmunity Meta-Analysis | It is associated with elevated anti-thyroid peroxidase antibodies (TPOAb) and often anti-thyroglobulin antibodies (TgAb) (). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
| Selenium Thyroid Autoimmunity Meta-Analysis | The incidence of HT has increased over recent decades and is higher with advancing age, in women, and in iodine-sufficient populations (,). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
| Selenium Thyroid Autoimmunity Meta-Analysis | Wet cupping was associated with a statistically significant reduction in anti-thyroid autoantibody levels and a decrease in TSH despite stable thyroid hormone dosing (). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
| Selenium Thyroid Autoimmunity Meta-Analysis | 1 2 3 4 Hashimoto’s thyroiditis (HT) is an autoimmune disorder that has been well documented as the leading cause of hypothyroidism and the most common form of thyroiditis (). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
Source documents