topicSelenium Sleep Randomized Trial
claimHypertension represents the predominant risk factor for cardiovascular disease morbidity and mortality; with significant healthcare utilization and expenditure.
evidence level2
citationSinclair J (2026)
sourceEffects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial.
topicSelenium Sleep Randomized Trial
claimGiven the substantial health and economic burden associated with hypertension worldwide, these findings suggest that twice-daily peppermint supplementation may represent a simple, low-cost, and well-tolerated strategy to support blood pressure reduction in this population.
evidence level2
citationSinclair J (2026)
sourceEffects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial.
topicSelenium Sleep Randomized Trial
claimPharmaceutical management is habitually adopted; although its long-term effectiveness remains ambiguous, and accompanying adverse effects are disquieting.
evidence level2
citationSinclair J (2026)
sourceEffects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial.
topicSelenium Sleep Randomized Trial
claimResults : The mean THI score decreased from 40.8 at baseline to 30.9 at the end of the study ( p = 0.012), and the percentage of patients with THI grade 1 (no handicap) increased from 3.3% to 20%.
evidence level3
citationCepeda Uceta M (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study.
topicSelenium Sleep Randomized Trial
claimA decrease in the mean frequency of tinnitus from 2417.4 Hz to 1603.3 Hz ( p = 0.519) was found.
evidence level3
citationCepeda Uceta M (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study.
topicSelenium Sleep Randomized Trial
claimConclusions : The administration of a natural-based dietary supplement composed of L-theanine, Ginkgo biloba , melatonin, GABA, zinc, selenium, and group B vitamins during 90 days in patients with tinnitus was associated with a significant increase in QoL by reducing tinnitus-associated handicap and anxiety.
evidence level3
citationCepeda Uceta M (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study.
topicSelenium Sleep Randomized Trial
claimBackground/Objectives : The objective of the study was to assess the benefits on quality of life (QoL) of a natural-based dietary supplement in patients with tinnitus.
evidence level3
citationCepeda Uceta M (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study.