topicSelenium Sleep Quality Randomized Trial
claimHypertension represents the predominant risk factor for cardiovascular disease morbidity and mortality; with significant healthcare utilization and expenditure.
evidence level2
citationSinclair J (2026)
sourceEffects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial.
topicSelenium Sleep Quality Randomized Trial
claimGiven the substantial health and economic burden associated with hypertension worldwide, these findings suggest that twice-daily peppermint supplementation may represent a simple, low-cost, and well-tolerated strategy to support blood pressure reduction in this population.
evidence level2
citationSinclair J (2026)
sourceEffects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial.
topicSelenium Sleep Quality Randomized Trial
claimPharmaceutical management is habitually adopted; although its long-term effectiveness remains ambiguous, and accompanying adverse effects are disquieting.
evidence level2
citationSinclair J (2026)
sourceEffects of peppermint (Mentha x piperita L.) oil on cardiometabolic outcomes in patients with pre- and stage 1 hypertension: A placebo randomized controlled trial.
topicSelenium Sleep Quality Randomized Trial
claimHowever, tinnitus is a heterogeneous condition with patients presenting a variety of overlapping symptoms and phenotypes related to the auditory component and the associated suffering characterized by psychological distress, sleep problems, concentration difficulties, behavioral changes, and functional impairment [,].
evidence level3
citationCepeda Uceta Massiel (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
topicSelenium Sleep Quality Randomized Trial
claimIn a systematic review based on five randomized controlled trials (RCTs), it was concluded that a standardizedextract is an evidence-based treatment option in tinnitus [].
evidence level3
citationCepeda Uceta Massiel (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
topicSelenium Sleep Quality Randomized Trial
claimReduced intake of vitamins B12, B6 and B3 may be associated with tinnitus-related annoyance and different studies have shown improvement in symptoms after B-complex vitamins supplementation [,].
evidence level3
citationCepeda Uceta Massiel (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
topicSelenium Sleep Quality Randomized Trial
claim1 2 3 4 5 6 7 8 Tinnitus, the perception of sound in the absence of an outside source, is a complex multifactorial problem that affects more than 740 million adults globally [] and can be considered a disability when it substantially and persistently impairs daily activities and quality of life [].
evidence level3
citationCepeda Uceta Massiel (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study