Structured evidence table for Selenium Mood Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Selenium Mood Randomized Trial | Both thyroidectomy and radioactive iodine therapy frequently induce iatrogenic hypothyroidism, leading to persistent cognitive slowing, low mood, and fatigue, while the psychological burden of cancer increases the risk of anxiety and depressive symptoms (,). | 3 | Zhang Zihan (2026) | Plant-derived nutritional components in thyroid disease-related neuropsychiatric disorders: mechanistic insights and advances |
| Selenium Mood Randomized Trial | Nutritional factors such as iodine and selenium have been investigated in relation to thyroid cancer risk, but epidemiological findings remain inconsistent, and the influence of cruciferous vegetables on thyroid function or thyroid cancer risk is similarly controversial, with current evidence still limited (,). | 3 | Zhang Zihan (2026) | Plant-derived nutritional components in thyroid disease-related neuropsychiatric disorders: mechanistic insights and advances |
| Selenium Mood Randomized Trial | The evidence base for many of these interventions remains limited, uneven, or derived from non-thyroid populations (). | 3 | Zhang Zihan (2026) | Plant-derived nutritional components in thyroid disease-related neuropsychiatric disorders: mechanistic insights and advances |
| Selenium Mood Randomized Trial | 1 2 3 4 Thyroid disorders are a unique intersection of endocrine and neurological health, and they are among the most widespread endocrine diseases worldwide (,). | 3 | Zhang Zihan (2026) | Plant-derived nutritional components in thyroid disease-related neuropsychiatric disorders: mechanistic insights and advances |
| Selenium Mood Randomized Trial | It is associated with elevated anti-thyroid peroxidase antibodies (TPOAb) and often anti-thyroglobulin antibodies (TgAb) (). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
| Selenium Mood Randomized Trial | The incidence of HT has increased over recent decades and is higher with advancing age, in women, and in iodine-sufficient populations (,). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
| Selenium Mood Randomized Trial | Wet cupping was associated with a statistically significant reduction in anti-thyroid autoantibody levels and a decrease in TSH despite stable thyroid hormone dosing (). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
| Selenium Mood Randomized Trial | 1 2 3 4 Hashimoto’s thyroiditis (HT) is an autoimmune disorder that has been well documented as the leading cause of hypothyroidism and the most common form of thyroiditis (). | 4 | Personius Lydia (2026) | Beyond levothyroxine: a narrative review of adjunctive management strategies for Hashimoto’s thyroiditis |
Source documents