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Selenium Anxiety Randomized Trial Evidence Table

Structured evidence table for Selenium Anxiety Randomized Trial, generated from 3 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Selenium Anxiety Randomized TrialHowever, tinnitus is a heterogeneous condition with patients presenting a variety of overlapping symptoms and phenotypes related to the auditory component and the associated suffering characterized by psychological distress, sleep problems, concentration difficulties, behavioral changes, and functional impairment [,].3Cepeda Uceta Massiel (2026)Benefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
Selenium Anxiety Randomized TrialIn a systematic review based on five randomized controlled trials (RCTs), it was concluded that a standardizedextract is an evidence-based treatment option in tinnitus [].3Cepeda Uceta Massiel (2026)Benefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
Selenium Anxiety Randomized TrialReduced intake of vitamins B12, B6 and B3 may be associated with tinnitus-related annoyance and different studies have shown improvement in symptoms after B-complex vitamins supplementation [,].3Cepeda Uceta Massiel (2026)Benefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
Selenium Anxiety Randomized Trial1 2 3 4 5 6 7 8 Tinnitus, the perception of sound in the absence of an outside source, is a complex multifactorial problem that affects more than 740 million adults globally [] and can be considered a disability when it substantially and persistently impairs daily activities and quality of life [].3Cepeda Uceta Massiel (2026)Benefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
Selenium Anxiety Randomized TrialIn age- and sex-adjusted analyses, lower magnesium and selenium levels were independently associated with palpitations.3Erden D (2026)Micronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.
Selenium Anxiety Randomized TrialConclusions : Subclinical differences in micronutrient status, particularly magnesium and selenium, together with increased anxiety, may contribute to non-structural palpitations in adolescents.3Erden D (2026)Micronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.
Selenium Anxiety Randomized TrialBackground : Palpitations are common in adolescents and often occur without structural heart disease.3Erden D (2026)Micronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.
Selenium Anxiety Randomized TrialAlthough anxiety and autonomic dysregulation have been implicated, the role of micronutrient status remains unclear.3Erden D (2026)Micronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.
Selenium Anxiety Randomized TrialHowever, the colocalization analysis did not provide any evidence of shared causal variants between supplementation with vitamin C, magnesium, selenium, and anxiety disorders.3Fang X (2025)Causal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.
Selenium Anxiety Randomized TrialAnalysis of the FAERS database showed that vitamin C (ROR: 0.30, 95% CI: 0.16-0.59, p = 0.0002) and magnesium use (ROR: 0.32, 95% CI: 0.18-0.57, p < 0.0001) were associated with decreased risks of anxiety; while no cases of anxiety were reported for selenium use.3Fang X (2025)Causal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.
Selenium Anxiety Randomized TrialOur study provides suggestive genetic evidence of the causal protective role of vitamin C, magnesium, and selenium on the risk of anxiety and supports targeting anxiety phenotypes with nutritional interventions.3Fang X (2025)Causal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.
Selenium Anxiety Randomized TrialAn increasing number of studies have begun to focus on the role of micronutrients (vitamins and minerals) in mental disorders, including anxiety.3Fang X (2025)Causal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.
topicSelenium Anxiety Randomized Trial
claimHowever, tinnitus is a heterogeneous condition with patients presenting a variety of overlapping symptoms and phenotypes related to the auditory component and the associated suffering characterized by psychological distress, sleep problems, concentration difficulties, behavioral changes, and functional impairment [,].
evidence level3
citationCepeda Uceta Massiel (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
topicSelenium Anxiety Randomized Trial
claimIn a systematic review based on five randomized controlled trials (RCTs), it was concluded that a standardizedextract is an evidence-based treatment option in tinnitus [].
evidence level3
citationCepeda Uceta Massiel (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
topicSelenium Anxiety Randomized Trial
claimReduced intake of vitamins B12, B6 and B3 may be associated with tinnitus-related annoyance and different studies have shown improvement in symptoms after B-complex vitamins supplementation [,].
evidence level3
citationCepeda Uceta Massiel (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
topicSelenium Anxiety Randomized Trial
claim1 2 3 4 5 6 7 8 Tinnitus, the perception of sound in the absence of an outside source, is a complex multifactorial problem that affects more than 740 million adults globally [] and can be considered a disability when it substantially and persistently impairs daily activities and quality of life [].
evidence level3
citationCepeda Uceta Massiel (2026)
sourceBenefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
topicSelenium Anxiety Randomized Trial
claimIn age- and sex-adjusted analyses, lower magnesium and selenium levels were independently associated with palpitations.
evidence level3
citationErden D (2026)
sourceMicronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.
topicSelenium Anxiety Randomized Trial
claimConclusions : Subclinical differences in micronutrient status, particularly magnesium and selenium, together with increased anxiety, may contribute to non-structural palpitations in adolescents.
evidence level3
citationErden D (2026)
sourceMicronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.
topicSelenium Anxiety Randomized Trial
claimBackground : Palpitations are common in adolescents and often occur without structural heart disease.
evidence level3
citationErden D (2026)
sourceMicronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.
topicSelenium Anxiety Randomized Trial
claimAlthough anxiety and autonomic dysregulation have been implicated, the role of micronutrient status remains unclear.
evidence level3
citationErden D (2026)
sourceMicronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.
topicSelenium Anxiety Randomized Trial
claimHowever, the colocalization analysis did not provide any evidence of shared causal variants between supplementation with vitamin C, magnesium, selenium, and anxiety disorders.
evidence level3
citationFang X (2025)
sourceCausal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.
topicSelenium Anxiety Randomized Trial
claimAnalysis of the FAERS database showed that vitamin C (ROR: 0.30, 95% CI: 0.16-0.59, p = 0.0002) and magnesium use (ROR: 0.32, 95% CI: 0.18-0.57, p < 0.0001) were associated with decreased risks of anxiety; while no cases of anxiety were reported for selenium use.
evidence level3
citationFang X (2025)
sourceCausal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.
topicSelenium Anxiety Randomized Trial
claimOur study provides suggestive genetic evidence of the causal protective role of vitamin C, magnesium, and selenium on the risk of anxiety and supports targeting anxiety phenotypes with nutritional interventions.
evidence level3
citationFang X (2025)
sourceCausal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.
topicSelenium Anxiety Randomized Trial
claimAn increasing number of studies have begun to focus on the role of micronutrients (vitamins and minerals) in mental disorders, including anxiety.
evidence level3
citationFang X (2025)
sourceCausal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.

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Source documents

  1. Benefits of a Natural Dietary Supplement for Tinnitus: An Observational Prospective Exploratory Study
  2. Micronutrient Profiles and Anxiety in Adolescents with Non-Structural Palpitations: A Case-Control Study.
  3. Causal Influences of Micronutrients on Anxiety: Insights From an Observational and Mendelian Randomization Analysis.