topicResveratrol Metabolic Health Randomized Trial
claimObesity, defined as excessive accumulation of adipose tissue, is strongly associated with metabolic complications, including hypertension, dyslipidemia, and type 2 diabetes [,].
evidence level1
citationGazda Patrycja (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review
topicResveratrol Metabolic Health Randomized Trial
claimChronic low-grade inflammation associated with obesity contributes to metabolic dysfunction through the increased production of pro-inflammatory cytokines and adipocytokines [].
evidence level1
citationGazda Patrycja (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review
topicResveratrol Metabolic Health Randomized Trial
claim5 6 7 8 9 10 11 Studies show that obesity significantly increases the risk of chronic diseases, including type 2 diabetes, cardiovascular disease, hypertension, dyslipidemia, hyperuricemia, and insulin resistance [,].
evidence level1
citationGazda Patrycja (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review
topicResveratrol Metabolic Health Randomized Trial
claim1 2 3 4 Metabolic disorders pose a serious challenge to healthcare systems worldwide due to their significant impact on quality of life, requiring a holistic approach in the context of prevention, diagnosis, and treatment.
evidence level1
citationGazda Patrycja (2026)
sourceThe Role of Anthocyanins, Curcumin, and Resveratrol in the Prevention and Management of Metabolic Disorders: A Systematic Review
topicResveratrol Metabolic Health Randomized Trial
claimAs a result, no phenotype-defined interventional evidence specific to sarcopenic obesity was identified.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Metabolic Health Randomized Trial
claimConclusion Despite compelling mechanistic convergence, randomized interventional evidence in strictly defined sarcopenic obesity populations is currently lacking.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Metabolic Health Randomized Trial
claimBackground Sarcopenic obesity (SO) is an inflammatory-metabolic condition characterized by the coexistence of excess adiposity and impaired skeletal muscle mass and function.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.
topicResveratrol Metabolic Health Randomized Trial
claimVitamin D and resveratrol modulate regulatory pathways implicated in SO pathophysiology, including NF-κB signaling, PGC-1α, mitochondrial regulation, and redox balance.
evidence level1
citationRusso C (2026)
sourceVitamin D and resveratrol in sarcopenic obesity: a systematic review highlighting the gap in phenotype-defined randomized controlled trials.