Structured evidence table for Quercetin Anxiety Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Quercetin Anxiety Randomized Trial | Furthermore, MDD is linked to a higher risk of developing other conditions like diabetes, heart disease, and stroke, which add to its overall impact on health (). | 3 | Zhu Shiyu (2026) | Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy |
| Quercetin Anxiety Randomized Trial | Neuroimaging studies have identified key pathological features of MDD, including reduced structural volumes in both cortical and subcortical areas, decreased gray matter volume, and significant alterations in the size and density of microglial cells (,). | 3 | Zhu Shiyu (2026) | Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy |
| Quercetin Anxiety Randomized Trial | These changes are also associated with abnormal neurotransmitter regulation and disruptions in gut microbiota (). | 3 | Zhu Shiyu (2026) | Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy |
| Quercetin Anxiety Randomized Trial | 1 2 3 4 5 6 7 8 9 10 11 12 Major depressive disorder (MDD) is a prevalent psychiatric condition impacting approximately 185 million individuals worldwide (). | 3 | Zhu Shiyu (2026) | Exploring the potential of polyphenols in major depression: from molecular function to clinical therapy |
| Quercetin Anxiety Randomized Trial | 2 3 4 5 6 7 1 8 Flavonoids are a diverse class of plant-derived polyphenols found abundantly in fruits, vegetables, wine, tea, and cocoa [,,]. | 4 | Rosas-Sánchez Gilberto Uriel (2026) | Flavonoids as Modulators of Neuroinflammation in Affective Disorders: A Narrative Review |
| Quercetin Anxiety Randomized Trial | For example, curcumin, found in turmeric, has demonstrated neuroprotective, anti-inflammatory, antioxidant, and antidepressant effects [,]. | 4 | Rosas-Sánchez Gilberto Uriel (2026) | Flavonoids as Modulators of Neuroinflammation in Affective Disorders: A Narrative Review |
| Quercetin Anxiety Randomized Trial | It affects approximately 1–4% of the global population and is associated with significant functional impairment and increased mortality [,]. | 4 | Rosas-Sánchez Gilberto Uriel (2026) | Flavonoids as Modulators of Neuroinflammation in Affective Disorders: A Narrative Review |
| Quercetin Anxiety Randomized Trial | 1 Given the fundamental role of neuroinflammation in affective disorders, there is growing interest in natural compounds, particularly flavonoids and polyphenols, for their potential to modulate inflammation and support brain function []. | 4 | Rosas-Sánchez Gilberto Uriel (2026) | Flavonoids as Modulators of Neuroinflammation in Affective Disorders: A Narrative Review |
Source documents