Pycnogenol Exercise Performance Randomized Trial Evidence Table

Structured evidence table for Pycnogenol Exercise Performance Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Pycnogenol Exercise Performance Randomized TrialObjective To describe the distribution and day-to-day variability of EuroQol Visual Analogue Scale (EQ-VAS) values and to estimate a minimal important difference (MID) in adults with post-COVID-19 condition (PCC).2Kopp J (2026)Within-person variability and the minimal important difference of the EQ-VAS in adults with post-COVID-19 condition: a secondary analysis of data from a single-centre randomised controlled trial.
Pycnogenol Exercise Performance Randomized TrialDesign Secondary analysis of pooled EQ-VAS data from both arms of a 12-week randomised, placebo-controlled trial (PYCNOVID) of Pycnogenol (200 mg/day) versus placebo in adults with PCC.2Kopp J (2026)Within-person variability and the minimal important difference of the EQ-VAS in adults with post-COVID-19 condition: a secondary analysis of data from a single-centre randomised controlled trial.
Pycnogenol Exercise Performance Randomized TrialFigure 1 Thus, in the present review we aimed to summarize the preclinical and clinical evidence of selected nutraceuticals, focusing on biotin, flavonoids especially luteolin, folic acid, Huperzine A, Lion’s mane, olive oil polyphenols (oleuropein and hydroxytyrosol [HT]), and palmitoylethanolamide (PEA).3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
Pycnogenol Exercise Performance Randomized TrialThe present narrative review highlights current mechanistic insights, as well as evidence from experimental and clinical studies regarding their potential roles in supporting cognitive function, modulating neuroinflammation, and mitigating neurodegenerative processes.3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
Pycnogenol Exercise Performance Randomized TrialIt should be noted that the present work consists of a review and not a dosing guideline.3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
Pycnogenol Exercise Performance Randomized Trial1 1 Brain health is a multidimensional and evolving concept that is difficult to evaluate and quantify [].3Venetsanaki Vasiliki (2026)Natural Molecules for Brain Health and Resilience
topicPycnogenol Exercise Performance Randomized Trial
claimObjective To describe the distribution and day-to-day variability of EuroQol Visual Analogue Scale (EQ-VAS) values and to estimate a minimal important difference (MID) in adults with post-COVID-19 condition (PCC).
evidence level2
citationKopp J (2026)
sourceWithin-person variability and the minimal important difference of the EQ-VAS in adults with post-COVID-19 condition: a secondary analysis of data from a single-centre randomised controlled trial.
topicPycnogenol Exercise Performance Randomized Trial
claimDesign Secondary analysis of pooled EQ-VAS data from both arms of a 12-week randomised, placebo-controlled trial (PYCNOVID) of Pycnogenol (200 mg/day) versus placebo in adults with PCC.
evidence level2
citationKopp J (2026)
sourceWithin-person variability and the minimal important difference of the EQ-VAS in adults with post-COVID-19 condition: a secondary analysis of data from a single-centre randomised controlled trial.
topicPycnogenol Exercise Performance Randomized Trial
claimFigure 1 Thus, in the present review we aimed to summarize the preclinical and clinical evidence of selected nutraceuticals, focusing on biotin, flavonoids especially luteolin, folic acid, Huperzine A, Lion’s mane, olive oil polyphenols (oleuropein and hydroxytyrosol [HT]), and palmitoylethanolamide (PEA).
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicPycnogenol Exercise Performance Randomized Trial
claimThe present narrative review highlights current mechanistic insights, as well as evidence from experimental and clinical studies regarding their potential roles in supporting cognitive function, modulating neuroinflammation, and mitigating neurodegenerative processes.
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicPycnogenol Exercise Performance Randomized Trial
claimIt should be noted that the present work consists of a review and not a dosing guideline.
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience
topicPycnogenol Exercise Performance Randomized Trial
claim1 1 Brain health is a multidimensional and evolving concept that is difficult to evaluate and quantify [].
evidence level3
citationVenetsanaki Vasiliki (2026)
sourceNatural Molecules for Brain Health and Resilience

Source documents

  1. Within-person variability and the minimal important difference of the EQ-VAS in adults with post-COVID-19 condition: a secondary analysis of data from a single-centre randomised controlled trial.
  2. Natural Molecules for Brain Health and Resilience