topicPycnogenol Blood Pressure Meta-Analysis
claimWhile glycaemic control remains the cornerstone of type 2 diabetes (T2DM) management, hypoglycaemic medications are associated with side effects.
evidence level3
citationLi E (2025)
sourceThe efficacy and safety of herbal medicines for glycaemic control and insulin resistance in individuals with type 2 diabetes: an umbrella review.
topicPycnogenol Blood Pressure Meta-Analysis
claimQuality assessment was performed using A Measurement Tool to Assess Systematic Reviews Version 2 (AMSTAR 2) and certainty of evidence for the primary outcome was assessed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) approach.
evidence level3
citationLi E (2025)
sourceThe efficacy and safety of herbal medicines for glycaemic control and insulin resistance in individuals with type 2 diabetes: an umbrella review.
topicPycnogenol Blood Pressure Meta-Analysis
claimGinger, turmeric, and Jinlida granules significantly decreased HbA1c compared to placebo (mean differences (MD): -0.467%, -0.486%, -0.283%, respectively) with moderate to high certainty evidence.
evidence level3
citationLi E (2025)
sourceThe efficacy and safety of herbal medicines for glycaemic control and insulin resistance in individuals with type 2 diabetes: an umbrella review.
topicPycnogenol Blood Pressure Meta-Analysis
claimThis review aims to comprehensively evaluate the efficacy and safety of herbal medicines for T2DM.
evidence level3
citationLi E (2025)
sourceThe efficacy and safety of herbal medicines for glycaemic control and insulin resistance in individuals with type 2 diabetes: an umbrella review.
topicPycnogenol Blood Pressure Meta-Analysis
claimRhabdomyolysis can cause complications such as acute kidney injury (AKI), with common etiologies including strenuous exercise, trauma, medications, and toxins.
evidence level4
citationKermanshah A (2025)
sourceRhabdomyolysis Associated With Excess Pycnogenol (Maritime Pine Bark Extract): A Case Report.
topicPycnogenol Blood Pressure Meta-Analysis
claimGiven that creatine kinase (CK) levels of about 100,000 U/L are rare, this level of elevation may indicate the presence of an underlying contributor, such as excessive Pycnogenol intake, emphasizing the importance of taking a thorough patient history to identify factors that may otherwise be overlooked.
evidence level4
citationKermanshah A (2025)
sourceRhabdomyolysis Associated With Excess Pycnogenol (Maritime Pine Bark Extract): A Case Report.