Structured evidence table for Pterostilbene Cardiometabolic Randomized Trial, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Pterostilbene Cardiometabolic Randomized Trial | Structurally related to resveratrol (), pterostilbene possesses greater lipophilicity and metabolic stability, which contribute to improved pharmacokinetic properties, including enhanced oral bioavailability and membrane permeability [,]. | 3 | Leong Xin-Fang (2026) | Pterostilbene in Cardiovascular Diseases: From Molecular Mechanisms to Therapeutic Potential |
| Pterostilbene Cardiometabolic Randomized Trial | Heterogeneity in study design, disease models, dosing strategies, and experimental endpoints complicates the interpretation of the overall evidence base and its translational significance. | 3 | Leong Xin-Fang (2026) | Pterostilbene in Cardiovascular Diseases: From Molecular Mechanisms to Therapeutic Potential |
| Pterostilbene Cardiometabolic Randomized Trial | Therefore, this narrative review aims to critically examine the available evidence on the cardioprotective actions of pterostilbene, with emphasis on its molecular mechanisms, and therapeutic effects across in vitro and in vivo models, while also considering its translational potential and current limitations. | 3 | Leong Xin-Fang (2026) | Pterostilbene in Cardiovascular Diseases: From Molecular Mechanisms to Therapeutic Potential |
| Pterostilbene Cardiometabolic Randomized Trial | Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide and continues to impose a major clinical and public health burden. | 3 | Leong Xin-Fang (2026) | Pterostilbene in Cardiovascular Diseases: From Molecular Mechanisms to Therapeutic Potential |
| Pterostilbene Cardiometabolic Randomized Trial | Prospective cohort studies and randomized controlled trials suggest that higher intakes of anthocyanin-rich foods are associated with improved vascular function, lower blood pressure, and reduced risk of coronary events and CVD [,,,,,,]. | 3 | Jurja Sanda (2025) | Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention |
| Pterostilbene Cardiometabolic Randomized Trial | Clinical trials in various populations, ranging from healthy individuals to those with metabolic syndrome or elevated cardiometabolic risk, have reported improvements in surrogate markers of vascular health—including flow-mediated dilation (FMD), blood pressure, arterial stiffness, and circulating biomarkers of endothelial activation—after blueberry intake [,,,,,,,,,,,]. | 3 | Jurja Sanda (2025) | Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention |
| Pterostilbene Cardiometabolic Randomized Trial | Nevertheless, not all studies have shown consistent benefits, and heterogeneity in dose, formulation, study duration, and population characteristics complicates the translation of these findings into clear, evidence-based dietary recommendations [,,,,,]. | 3 | Jurja Sanda (2025) | Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention |
| Pterostilbene Cardiometabolic Randomized Trial | 1 2 3 4 5 6 7 8 9 10 10 11 12 Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide and is strongly driven by modifiable lifestyle factors, including diet, physical inactivity, smoking, and metabolic disorders such as hypertension, dyslipidemia, and type 2 diabetes [,,,,]. | 3 | Jurja Sanda (2025) | Blueberries and Honeysuckle Berries: Anthocyanin-Rich Polyphenols for Vascular Endothelial Health and Cardiovascular Disease Prevention |
Source documents