topicProtein Intake Muscle Meta-Analysis
claimThis review synthesizes current evidence on glucagon-like peptide-1 receptor agonists (GLP-1 RAs), a well-studied AOMs, focusing on their effects on sarcopenia through mechanistic insights and clinical considerations in older adults.
evidence level3
citationSimsek H (2026)
sourceGLP-1 Receptor Agonists for Obesity Management in Older Adults: A Scoping Review on the Risk of Sarcopenia and Sarcopenic Obesity.
topicProtein Intake Muscle Meta-Analysis
claimWeight cycling introduces uncertainty regarding skeletal muscle health and SO risk.
evidence level3
citationSimsek H (2026)
sourceGLP-1 Receptor Agonists for Obesity Management in Older Adults: A Scoping Review on the Risk of Sarcopenia and Sarcopenic Obesity.
topicProtein Intake Muscle Meta-Analysis
claimAlthough data on muscle mass indices and physical performance remain limited and inconsistent, evidence suggests favorable effects on muscle metabolism and composition.
evidence level3
citationSimsek H (2026)
sourceGLP-1 Receptor Agonists for Obesity Management in Older Adults: A Scoping Review on the Risk of Sarcopenia and Sarcopenic Obesity.
topicProtein Intake Muscle Meta-Analysis
claimPurpose of review Obesity pharmacotherapy has become increasingly relevant in older adults due to challenges in lifestyle modification and the burden of non-communicable diseases.
evidence level3
citationSimsek H (2026)
sourceGLP-1 Receptor Agonists for Obesity Management in Older Adults: A Scoping Review on the Risk of Sarcopenia and Sarcopenic Obesity.
topicProtein Intake Muscle Meta-Analysis
claimAccording to the internationally used definition, MetS is characterized by having at least three out of several possible risk factors, including high blood pressure, hypertriglyceridemia, low levels of HDL cholesterol, elevated fasting glucose, and central obesity ().
evidence level3
citationWang Song-nan (2026)
sourceBranched-chain amino acids from plants and the metabolic syndrome: pathways and pharmacological applications
topicProtein Intake Muscle Meta-Analysis
claimα p p 6 7 9 9 10 6 High levels of TNF-, IL-6, and CRP are associated with insulin resistance, endothelial dysfunction, and atherogenesis (,,).
evidence level3
citationWang Song-nan (2026)
sourceBranched-chain amino acids from plants and the metabolic syndrome: pathways and pharmacological applications
topicProtein Intake Muscle Meta-Analysis
claimSuch increases appear to be closely linked to MetS, type 2T2DM, and CVD risk (,).
evidence level3
citationWang Song-nan (2026)
sourceBranched-chain amino acids from plants and the metabolic syndrome: pathways and pharmacological applications
topicProtein Intake Muscle Meta-Analysis
claim1 1 The metabolic syndrome (MetS), one of the most significant public health problems of the 21st century, is characterized by central obesity, insulin resistance, hypertension, and dyslipidemia.
evidence level3
citationWang Song-nan (2026)
sourceBranched-chain amino acids from plants and the metabolic syndrome: pathways and pharmacological applications