Structured evidence table for Probiotics Skin Acne Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Probiotics Skin Acne Meta-Analysis | Its multifactorial pathogenesis involves increased sebum production, follicular hyperkeratinization,colonization, and inflammatory immune responses []. | 1 | Abedin Zain Ul (2026) | Lactobacillus‐Based Microbiome Therapy for Acne Vulgaris: A GRADE Systematic Review and Meta‐Analysis of Randomized Controlled Trials |
| Probiotics Skin Acne Meta-Analysis | Beyond physical manifestations, acne also impairs psychosocial health, often leading to anxiety, depression, and reduced quality of life []. | 1 | Abedin Zain Ul (2026) | Lactobacillus‐Based Microbiome Therapy for Acne Vulgaris: A GRADE Systematic Review and Meta‐Analysis of Randomized Controlled Trials |
| Probiotics Skin Acne Meta-Analysis | While some studies reported significant reductions in inflammatory and non‐inflammatory lesions when compared with placebo or benzoyl peroxide, others found modest or non‐significant effects [,,]. | 1 | Abedin Zain Ul (2026) | Lactobacillus‐Based Microbiome Therapy for Acne Vulgaris: A GRADE Systematic Review and Meta‐Analysis of Randomized Controlled Trials |
| Probiotics Skin Acne Meta-Analysis | 1 2 3 4 5 Cutibacterium acnes Acne vulgaris is one of the most prevalent dermatological disorders, the eighth most common disease worldwide, affecting approximately 9%–10% of the global population []. | 1 | Abedin Zain Ul (2026) | Lactobacillus‐Based Microbiome Therapy for Acne Vulgaris: A GRADE Systematic Review and Meta‐Analysis of Randomized Controlled Trials |
| Probiotics Skin Acne Meta-Analysis | These treatments show varying degrees of efficacy and improved safety profiles, but most lack head-to-head comparisons with isotretinoin. | 4 | Tommasino N (2026) | Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate-to-Severe Acne. |
| Probiotics Skin Acne Meta-Analysis | Conclusion Several systemic options beyond isotretinoin have emerged, showing potential in specific subgroups or as adjunctive therapies. | 4 | Tommasino N (2026) | Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate-to-Severe Acne. |
| Probiotics Skin Acne Meta-Analysis | However, further large-scale comparative studies are needed to define their roles within evidence-based acne management algorithms. | 4 | Tommasino N (2026) | Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate-to-Severe Acne. |
| Probiotics Skin Acne Meta-Analysis | Background Acne vulgaris is a common inflammatory skin disorder with significant psychosocial impact. | 4 | Tommasino N (2026) | Beyond Isotretinoin: A Narrative Review of Emerging Systemic Therapies for Moderate-to-Severe Acne. |
Source documents