Structured evidence table for Probiotics Migraine Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Probiotics Migraine Meta-Analysis | Migraine is a primary headache disorder affecting about 14% of the global population. | 1 | Grodzka O (2025) | Gut microbiota, probiotics, and migraine: a clinical review and meta-analysis. |
| Probiotics Migraine Meta-Analysis | The knowledge about migraine pathophysiology is increasing constantly; however, there are still many unknowns and uncertainties. | 1 | Grodzka O (2025) | Gut microbiota, probiotics, and migraine: a clinical review and meta-analysis. |
| Probiotics Migraine Meta-Analysis | In addition to its high prevalence and disability burden, migraine is associated with substantial socioeconomic costs, with estimated direct and indirect expenditures of approximately USD 36 billion annually in the United States []. | 3 | Kozák Márk (2026) | Migraine and the Gut–Brain Axis—The Role of Microbiome-Targeted Biotics |
| Probiotics Migraine Meta-Analysis | Clinically, migraine is characterized by recurrent attacks of moderate-to-severe headache lasting 4–72 h, typically unilateral and pulsating, aggravated by routine physical activity, and frequently accompanied by photophobia and phonophobia; in a substantial subset of patients, attacks are associated with reversible focal neurological symptoms called aura. | 3 | Kozák Márk (2026) | Migraine and the Gut–Brain Axis—The Role of Microbiome-Targeted Biotics |
| Probiotics Migraine Meta-Analysis | 6 7 8 9 10 11 12 2 13 14 10 15 16 Helicobacter pylori The most common gastrointestinal disorders associated with migraine are irritable bowel syndrome (IBS) (reported in up to 50% of patients with migraine []), inflammatory bowel disease (IBD) [,,], gastroesophageal reflux disease (GERD) [], functional dyspepsia [,], cyclic vomiting syndrome [], peptic ulcers andinfections [,]. | 3 | Kozák Márk (2026) | Migraine and the Gut–Brain Axis—The Role of Microbiome-Targeted Biotics |
| Probiotics Migraine Meta-Analysis | 1 2 3 4 2 3 5 Migraine is a prevalent primary headache disorder with significant morbidity and rising prevalence, affecting around 14% of the global population []. | 3 | Kozák Márk (2026) | Migraine and the Gut–Brain Axis—The Role of Microbiome-Targeted Biotics |
Source documents