Structured evidence table for Probiotic Digestive Symptoms Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Probiotic Digestive Symptoms Meta-Analysis | To synthesize the available evidence, multiple systematic reviews with meta-analyses have been published [,,,,,,,,,,,,,,,,,,,,,,,,,,,,,] (). | 1 | Maslennikov Roman (2026) | Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome |
| Probiotic Digestive Symptoms Meta-Analysis | In accordance with the principles of evidence-based medicine, meta-analyses of randomized placebo-controlled trials (RPCTs) provide the highest level of evidence, as they minimize bias and allow an assessment of the reproducibility of results. | 1 | Maslennikov Roman (2026) | Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome |
| Probiotic Digestive Symptoms Meta-Analysis | 54 The risk of bias of the included studies was assessed using the Cochrane Risk of Bias 2 (RoB 2) tool []. | 1 | Maslennikov Roman (2026) | Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome |
| Probiotic Digestive Symptoms Meta-Analysis | 1 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 Supplementary Table S1 Irritable bowel syndrome (IBS) is one of the most common gastrointestinal disorders worldwide []. | 1 | Maslennikov Roman (2026) | Strain-Specific Systematic Review with Meta-Analysis of Probiotics Efficacy in the Treatment of Irritable Bowel Syndrome |
| Probiotic Digestive Symptoms Meta-Analysis | This review adopts a systems-level perspective to synthesize emerging evidence on probiotic-driven gut–brain, gut–skin, gut–oral, and metabolic interactions, emphasizing shared mechanisms rather than isolated clinical outcomes. | 3 | Zalila-Kolsi Imen (2026) | Probiotics and the Human Microbiome: Classical Functions, Emerging Systemic Roles, and Future Therapeutic Frontiers |
| Probiotic Digestive Symptoms Meta-Analysis | In parallel, advances in encapsulation and delivery technologies have improved probiotic survival during gastrointestinal transit, thereby enhancing their functional efficacy within the gut. | 3 | Zalila-Kolsi Imen (2026) | Probiotics and the Human Microbiome: Classical Functions, Emerging Systemic Roles, and Future Therapeutic Frontiers |
| Probiotic Digestive Symptoms Meta-Analysis | rhamnosus 14 16 Functionally, experimental and clinical studies indicate that strain-specificspecies, such as,, and, regulate gut motility and carbohydrate metabolism, contributing to improved lactose digestion and alleviation of constipation and bloating []. | 3 | Zalila-Kolsi Imen (2026) | Probiotics and the Human Microbiome: Classical Functions, Emerging Systemic Roles, and Future Therapeutic Frontiers |
| Probiotic Digestive Symptoms Meta-Analysis | 1 2 3 4 5 Lactobacillus Bifidobacterium Enterococcus Streptococcus Saccharomyces boulardii, The term “probiotics,” which comes from the Greek word “for life,” refers to live microorganisms that, when given in sufficient quantities, promote the host’s health []. | 3 | Zalila-Kolsi Imen (2026) | Probiotics and the Human Microbiome: Classical Functions, Emerging Systemic Roles, and Future Therapeutic Frontiers |
Source documents