topicProbiotic Depression Meta-Analysis
claimThe microbiota-gut-brain axis suggests probiotics and synbiotics could modulate sleep, but evidence in exercised populations is limited.
evidence level1
citationSalehi Asl M (2026)
sourceThe effect of probiotic and synbiotic supplementation on sleep parameters in exercised population: a systematic review and synthesis without meta-analysis (SWiM) of randomized controlled trials.
topicProbiotic Depression Meta-Analysis
claimData extraction, risk of bias assessment (RoB 2), and narrative synthesis followed SWiM guidelines.
evidence level1
citationSalehi Asl M (2026)
sourceThe effect of probiotic and synbiotic supplementation on sleep parameters in exercised population: a systematic review and synthesis without meta-analysis (SWiM) of randomized controlled trials.
topicProbiotic Depression Meta-Analysis
claimNine of twelve primary sleep outcomes favored supplementation, with significant effects for probiotics (combined p p Conclusion Probiotic and synbiotic supplementation may improve sleep in exercised populations, especially perceived quality and latency.
evidence level1
citationSalehi Asl M (2026)
sourceThe effect of probiotic and synbiotic supplementation on sleep parameters in exercised population: a systematic review and synthesis without meta-analysis (SWiM) of randomized controlled trials.
topicProbiotic Depression Meta-Analysis
claimBackground Sleep is crucial for recovery and optimal performance in athletes; however, poor sleep is common during periods of intensive training or competition.
evidence level1
citationSalehi Asl M (2026)
sourceThe effect of probiotic and synbiotic supplementation on sleep parameters in exercised population: a systematic review and synthesis without meta-analysis (SWiM) of randomized controlled trials.
topicProbiotic Depression Meta-Analysis
claimProbiotic monotherapy was associated with a small but statistically significant reduction in depressive symptoms (SMD = -0.38, 95% CI: -0.57 to -0.18, p = 0.0002, I² = 51%).
evidence level1
citationHaiyan L (2026)
sourceEfficacy of probiotic intervention in unmedicated depression: a systematic review and meta-analysis.
topicProbiotic Depression Meta-Analysis
claimConclusion Probiotic monotherapy may provide modest improvement in depressive symptoms and is generally safe for unmedicated individuals with mild to moderate depression.
evidence level1
citationHaiyan L (2026)
sourceEfficacy of probiotic intervention in unmedicated depression: a systematic review and meta-analysis.
topicProbiotic Depression Meta-Analysis
claimObjective To assess the independent efficacy and safety of probiotics in unmedicated adults with depression, with a focus on studies approximating monotherapy conditions.
evidence level1
citationHaiyan L (2026)
sourceEfficacy of probiotic intervention in unmedicated depression: a systematic review and meta-analysis.
topicProbiotic Depression Meta-Analysis
claimMethods This systematic review and meta-analysis followed PRISMA 2020 guidelines and was registered with PROSPERO (CRD420251015474).
evidence level1
citationHaiyan L (2026)
sourceEfficacy of probiotic intervention in unmedicated depression: a systematic review and meta-analysis.