evidence table
Probiotic Depression Meta-Analysis Evidence Table
Structured evidence table for Probiotic Depression Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Probiotic Depression Meta-Analysis | The microbiota-gut-brain axis suggests probiotics and synbiotics could modulate sleep, but evidence in exercised populations is limited. | 1 | Salehi Asl M (2026) | The effect of probiotic and synbiotic supplementation on sleep parameters in exercised population: a systematic review and synthesis without meta-analysis (SWiM) of randomized controlled trials. |
| Probiotic Depression Meta-Analysis | Data extraction, risk of bias assessment (RoB 2), and narrative synthesis followed SWiM guidelines. | 1 | Salehi Asl M (2026) | The effect of probiotic and synbiotic supplementation on sleep parameters in exercised population: a systematic review and synthesis without meta-analysis (SWiM) of randomized controlled trials. |
| Probiotic Depression Meta-Analysis | Nine of twelve primary sleep outcomes favored supplementation, with significant effects for probiotics (combined p p Conclusion Probiotic and synbiotic supplementation may improve sleep in exercised populations, especially perceived quality and latency. | 1 | Salehi Asl M (2026) | The effect of probiotic and synbiotic supplementation on sleep parameters in exercised population: a systematic review and synthesis without meta-analysis (SWiM) of randomized controlled trials. |
| Probiotic Depression Meta-Analysis | Background Sleep is crucial for recovery and optimal performance in athletes; however, poor sleep is common during periods of intensive training or competition. | 1 | Salehi Asl M (2026) | The effect of probiotic and synbiotic supplementation on sleep parameters in exercised population: a systematic review and synthesis without meta-analysis (SWiM) of randomized controlled trials. |
| Probiotic Depression Meta-Analysis | Probiotic monotherapy was associated with a small but statistically significant reduction in depressive symptoms (SMD = -0.38, 95% CI: -0.57 to -0.18, p = 0.0002, I² = 51%). | 1 | Haiyan L (2026) | Efficacy of probiotic intervention in unmedicated depression: a systematic review and meta-analysis. |
| Probiotic Depression Meta-Analysis | Conclusion Probiotic monotherapy may provide modest improvement in depressive symptoms and is generally safe for unmedicated individuals with mild to moderate depression. | 1 | Haiyan L (2026) | Efficacy of probiotic intervention in unmedicated depression: a systematic review and meta-analysis. |
| Probiotic Depression Meta-Analysis | Objective To assess the independent efficacy and safety of probiotics in unmedicated adults with depression, with a focus on studies approximating monotherapy conditions. | 1 | Haiyan L (2026) | Efficacy of probiotic intervention in unmedicated depression: a systematic review and meta-analysis. |
| Probiotic Depression Meta-Analysis | Methods This systematic review and meta-analysis followed PRISMA 2020 guidelines and was registered with PROSPERO (CRD420251015474). | 1 | Haiyan L (2026) | Efficacy of probiotic intervention in unmedicated depression: a systematic review and meta-analysis. |
Source documents