topicProbiotic Constipation Meta-Analysis
claimThe authors did a good job of summarizing a large body of evidence, and their conclusion that probiotics help with childhood diarrhea agrees with the general scientific opinion.
evidence level1
citationPeng Yue (2026)
sourceCommentary: The effect of probiotics on the diarrhea and constipation outcomes in children: an umbrella review of systematic reviews and meta-analyses
topicProbiotic Constipation Meta-Analysis
claimAs a result, the total sample size is inflated, which narrows the confidence intervals for the summary effect estimate.
evidence level1
citationPeng Yue (2026)
sourceCommentary: The effect of probiotics on the diarrhea and constipation outcomes in children: an umbrella review of systematic reviews and meta-analyses
topicProbiotic Constipation Meta-Analysis
claimThis makes the results seem more precise than they actually are and can lead to misleadingly low-values, increasing the risk of a Type I error (false positive).
evidence level1
citationPeng Yue (2026)
sourceCommentary: The effect of probiotics on the diarrhea and constipation outcomes in children: an umbrella review of systematic reviews and meta-analyses
topicProbiotic Constipation Meta-Analysis
claimThe effect of probiotics on the diarrhea and constipation outcomes in children: an umbrella review of systematic reviews and meta-analyses 1 We read with great interest the recent umbrella review by Wang et al., titled “” ().
evidence level1
citationPeng Yue (2026)
sourceCommentary: The effect of probiotics on the diarrhea and constipation outcomes in children: an umbrella review of systematic reviews and meta-analyses
topicProbiotic Constipation Meta-Analysis
claimThis review summarizes the current concepts of probiotics and evaluates evidence supporting their use in patients with lower GI disorders, with a focus on potential sex-related differences.
evidence level2
citationKim Yong Sung (2026)
sourceClinical Guidance and Practical Recommendations for Probiotic Use in Patients With Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-based Differences
topicProbiotic Constipation Meta-Analysis
claimSaccharomyces, Lactobacillus Bifidobacterium Clostridium difficile 7 This review was conducted to summarize and interpret the current evidence on probiotics on IBS, FC, and CDI in terms of sex differences.
evidence level2
citationKim Yong Sung (2026)
sourceClinical Guidance and Practical Recommendations for Probiotic Use in Patients With Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-based Differences
topicProbiotic Constipation Meta-Analysis
claimOverall, probiotics significantly increased spontaneous bowel movement (SBM) per week by 0.67 (95% CI, 0.22-1.12) at 4 weeks after ingestion ().
evidence level2
citationKim Yong Sung (2026)
sourceClinical Guidance and Practical Recommendations for Probiotic Use in Patients With Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-based Differences
topicProbiotic Constipation Meta-Analysis
claimClostridioides difficile 1 3 - 4 5 4 6 - For over a century, probiotics have been widely consumed as fermented beverages and supplements to promote gut health.
evidence level2
citationKim Yong Sung (2026)
sourceClinical Guidance and Practical Recommendations for Probiotic Use in Patients With Irritable Bowel Syndrome, Functional Constipation, and Clostridioides difficile Infection Considering Sex-based Differences