Probiotic Anxiety Meta-Analysis Evidence Table

Structured evidence table for Probiotic Anxiety Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.

topicclaimevidence levelcitationsource
Probiotic Anxiety Meta-AnalysisMoreover, the probiotic interventions were associated with a statistically significant reduction in cortisol levels, a key biomarker of physiological stress (SMD = -0.26, 95% confidence interval [CI] [-0.45, -0.08], p = 0.005).1Ben Fredj S (2026)Probiotic intake and mental health in healthy working adults: a systematic review and meta-analysis of randomized controlled trials.
Probiotic Anxiety Meta-AnalysisHowever, due to the lack of available evidence, it was impossible to draw firm conclusions about the effects of probiotics on sleep quality and biomarkers of oxidative stress.1Ben Fredj S (2026)Probiotic intake and mental health in healthy working adults: a systematic review and meta-analysis of randomized controlled trials.
Probiotic Anxiety Meta-AnalysisConclusion This systematic review and meta-analysis provide preliminary evidence suggesting that probiotic supplementation may hold promise as an approach to improve mental well-being within working populations.1Ben Fredj S (2026)Probiotic intake and mental health in healthy working adults: a systematic review and meta-analysis of randomized controlled trials.
Probiotic Anxiety Meta-AnalysisBackground Workers face significant mental health challenges from stress, anxiety, and depression, impacting individuals, organizations, and society.1Ben Fredj S (2026)Probiotic intake and mental health in healthy working adults: a systematic review and meta-analysis of randomized controlled trials.
Probiotic Anxiety Meta-Analysis15 16 17 19 20 21 22 23 24 The emerging evidence supports that there is a bidirectional relationship between gut microbiota and depression, representing a paradigm shift in psychiatric research [,].2Mosavat Seyed Hamdollah (2026)Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial
Probiotic Anxiety Meta-AnalysisAnimal studies have presented some compelling evidence to suggest a causal role of dysbiosis in depression-like behaviours [].2Mosavat Seyed Hamdollah (2026)Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial
Probiotic Anxiety Meta-AnalysisMDD and SUD often co-occur, with each disorder increasing the risk of developing the other [].2Mosavat Seyed Hamdollah (2026)Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial
Probiotic Anxiety Meta-Analysis1 2 3 4 5 Major Depressive Disorder (MDD) is one of the most frequent and disabling psychiatric conditions worldwide, and recent estimates suggest that there are 300 million1 cases [].2Mosavat Seyed Hamdollah (2026)Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial

Source documents

  1. Probiotic intake and mental health in healthy working adults: a systematic review and meta-analysis of randomized controlled trials.
  2. Effect of probiotic supplement on improvement of depressive symptoms in patients with substance-induced depressive disorder: a randomized, double-blind, placebo-controlled clinical trial