Structured evidence table for Probiotic Acne Meta-Analysis, generated from 2 reusable source documents in the Migaku knowledge base.
| topic | claim | evidence level | citation | source |
|---|---|---|---|---|
| Probiotic Acne Meta-Analysis | Background Acne vulgaris is one of the most prevalent disorders affecting 9%-10% of the global population, representing as papules, pustules, and comedones, with a pathogenesis involving increased sebum production, C. | 1 | Abedin ZU (2026) | Lactobacillus-Based Microbiome Therapy for Acne Vulgaris: A GRADE Systematic Review and Meta-Analysis of Randomized Controlled Trials. |
| Probiotic Acne Meta-Analysis | The findings aim to clarify their therapeutic role and provide evidence on their effectiveness and safety. | 1 | Abedin ZU (2026) | Lactobacillus-Based Microbiome Therapy for Acne Vulgaris: A GRADE Systematic Review and Meta-Analysis of Randomized Controlled Trials. |
| Probiotic Acne Meta-Analysis | Conclusion This meta-analysis indicates that Lactobacillus-based probiotics do not provide significant clinical benefits in reducing inflammatory lesions, non-inflammatory lesions, and total acne lesion counts in Acne vulgaris patients compared to placebo or benzoyl peroxide. | 1 | Abedin ZU (2026) | Lactobacillus-Based Microbiome Therapy for Acne Vulgaris: A GRADE Systematic Review and Meta-Analysis of Randomized Controlled Trials. |
| Probiotic Acne Meta-Analysis | Conventional treatments like retinoids and antibiotics often cause side effects, thus diverting attention toward probiotics as an alternative therapy. | 1 | Abedin ZU (2026) | Lactobacillus-Based Microbiome Therapy for Acne Vulgaris: A GRADE Systematic Review and Meta-Analysis of Randomized Controlled Trials. |
| Probiotic Acne Meta-Analysis | Four randomized controlled trials involving 227 participants were analyzed, showing that probiotic supplementation reduced acne severity scores (OR 0.48; 95% CI 0.29-0.79) and non-inflammatory lesion counts (mean difference (MD) -4.62; 95% CI -8.10 to -1.15) compared with controls. | 1 | Mohamed M (2025) | The Impact of Probiotics on Acne Vulgaris: A Meta-Analysis of Randomized Controlled Trials. |
| Probiotic Acne Meta-Analysis | Acne vulgaris is a multifactorial inflammatory skin disorder influenced by hormonal activity, microbial imbalance, and immune dysregulation. | 1 | Mohamed M (2025) | The Impact of Probiotics on Acne Vulgaris: A Meta-Analysis of Randomized Controlled Trials. |
| Probiotic Acne Meta-Analysis | While conventional treatments such as antibiotics and retinoids remain effective, their long-term use is often limited by side effects, resistance, and poor adherence. | 1 | Mohamed M (2025) | The Impact of Probiotics on Acne Vulgaris: A Meta-Analysis of Randomized Controlled Trials. |
Source documents